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Publications

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S. Ppublish 2 citations

PubMed: 30945620 DOI: 10.1080/19338244.2019.1577210

Anti-Müllerian hormone levels in nurses working night shifts.

Arch Environ Occup Health 75(3):136-143

Authors: Candice Y Johnson, Lauren J Tanz, Christina C Lawson, Penelope P Howards, Elizabeth R Bertone-Johnson, A Heather Eliassen, Eva S Schernhammer, Janet W Rich-Edwards

Affiliations

  • National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio, USA.
  • Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
  • Division of Women's Health, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
  • Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts, USA.
  • Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  • Department of Epidemiology, Medical University of Vienna, Vienna, Austria.
  • Connor Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

Abstract

Our objective was to examine associations between night shift work and serum anti-Müllerian hormone (AMH) levels. We analyzed 1,537 blood samples from premenopausal female nurses in the Nurses' Health Study II, assayed for AMH. Rotating or permanent night shifts worked in the two weeks before blood collection and years of rotating night shift work were obtained via questionnaire. We found no associations between recent night shifts or rotating night shift work and AMH. The median difference in AMH was 0.3 (95% CI: -0.4, 0.8) ng/mL for ≥5 versus 0 recent night shifts and -0.1 (95% CI: -0.4, 0.3) ng/mL for ≥6 versus 0 years of rotating night shift work. Although we found no associations between night shift work and AMH, this does not preclude associations between night shift work and fertility operating through other mechanisms.

MeSH

Nurses, Blood, Shift Work Schedule, Ovarian Reserve, Hormones, Work, Anti-Mullerian Hormone, Environmental Health