Journal Article Ppublish 9 citations
PubMed: 31134412 DOI: 10.1007/s10815-019-01490-1
Hypertensive disorders of pregnancy and infertility treatment: a population-based survey among United States women.
J Assist Reprod Genet 36(7):1449-1456
Authors: Brent C Monseur, Jerrine R Morris, Heather S Hipp, Vincenzo Berghella
Affiliations
- Department of Obstetrics & Gynecology, Sidney Kimmel Medical College, Thomas Jefferson University, 833 Chestnut Street, Suite 301, Philadelphia, PA, 19107, USA.
- Department of Gynecology and Obstetrics, Emory University School of Medicine, 550 Peachtree Street, Suite 1800, Atlanta, GA, 30308, USA.
- Division of Reproductive Endocrinology and Infertility, Emory University School of Medicine, 550 Peachtree Street, Suite 1800, Atlanta, GA, 30308, USA.
- Division of Maternal Fetal Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, 833 Chestnut Street, Philadelphia, PA, 19107, USA.
Abstract
PURPOSE
To explore associations between infertility treatment and hypertensive disorders of pregnancy.
METHODS
We collated multi-year as well as multi-state data from a national representative survey examining the association between self-reported infertility treatment (i.e., medication, intrauterine insemination, or assisted reproductive technology) and hypertensive disorders of pregnancy (i.e., high blood pressure, pregnancy-induced hypertension (PIH), preeclampsia, and toxemia). Data were analyzed using logistic regression. A total of 21,884 women in the United States (U.S.), from the Centers for Disease Control and Prevention's (CDC) Pregnancy Risk Assessment Monitoring System (PRAMS) survey (2009-2015), participated in the study.
RESULTS
In our analysis, 12.91% women reported a history of infertility treatment and 15.19% reported a history of hypertensive disorder of pregnancy. Compared with women who had never had infertility treatment, women who reported infertility treatment had 1.18 (adjusted OR, 95% confidence interval (CI) 1.05, 1.33) higher odds of reporting hypertensive disorder of pregnancy. Neither types of infertility treatment nor proximity of treatment to pregnancy were independently associated with hypertensive disorder of pregnancy.
CONCLUSIONS
Our results suggest that among U.S. women, the treatment of infertility may be associated with hypertension disorder of pregnancy regardless of type of treatment.
MeSH
Hypertension, Pregnancy, Genetics, Reproductive Techniques, Infertility, Multiple Chronic Conditions, Fertilization In Vitro, Embryo Transfer, Centers For Disease Control And Prevention, U.S., Therapeutics, History