Journal Article Review Epublish 24 citations
PubMed: 33499120 DOI: 10.3390/jcm10030414
Impact of Surgical Management of Endometrioma on AMH Levels and Pregnancy Rates: A Review of Recent Literature.
J Clin Med 10(3)
Authors: Ana Sofia Pais, Clara Flagothier, Linda Tebache, Teresa Almeida Santos, Michelle Nisolle
Affiliations
- Reproductive Medicine Unit, Centro Hospitalar e Universitário de Coimbra, 3004-561 Coimbra, Portugal.
- Obstetrics Department, Faculty of Medicine, University of Coimbra, 3000-370 Coimbra, Portugal.
- Coimbra Institute for Clinical and Biomedical Research (iCBR) Area of Environment Genetics and Oncobiology (CIMAGO), Biophysics Institute of Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.
- Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3000-548 Coimbra, Portugal.
- Clinical Academic Center of Coimbra (CACC), 3000-548 Coimbra, Portugal.
- Department of Obstetrics and Gynaecology, Hospital CHR Liège, University of Liège, 4000 Liège, Belgium.
- Faculty of Medicine, University of Coimbra, 3000-370 Coimbra, Portugal.
Abstract
Ovarian endometrioma are found in up to 40% of women with endometriosis and 50% of infertile women. The best surgical approach for endometrioma and its impact on pregnancy rates is still controversial. Therefore, we conducted a literature review on surgical management of ovarian endometrioma and its impact on pregnancy rates and ovarian reserve, assessed by anti-Müllerian hormone (AMH) serum levels. Ovarian cystectomy is the preferred technique, as it is associated with lower recurrence and higher spontaneous pregnancy rate. However, ablative approaches and combined techniques are becoming more popular as ovarian reserve is less affected and there are slightly higher pregnancy rates. Preoperative AMH level might be useful to predict the occurrence of pregnancy. In conclusion, AMH should be included in the preoperative evaluation of reproductive aged women with endometriosis. The surgical options for ovarian endometrioma should be individualized. The endometrioma ablation procedure seems to be the most promising treatment.
MeSH
Endometriosis, Pregnancy, Ovary, Ovarian Reserve, Pregnancy Rate
Cited by
- Efficacy of ablation and sclerotherapy for the management of ovarian endometrioma: A narrative review. Clin Exp Reprod Med, 2022
- Peritoneal Endometriosis Impairs Ovarian Reserve and Increases Atresia in a Rat Model. Biomedicines, 2025
- Conservative endometrioma surgery: The combined technique versus CO2-laser vaporization only (BLAST: Belgium LAser STudy): Clinical protocol for a multicenter randomized controlled trial. PLoS One, 2025
- Ovarian Endometrioma Negatively Impacts Oocyte Quality and Quantity But Not Pregnancy Outcomes in Women Undergoing IVF/ICSI Treatment: A Retrospective Cohort Study. Front Endocrinol (Lausanne), 2022
- Assisted Reproductive Technology Outcomes After Ethanol Sclerotherapy in Poor Responder Patients with Endometriomas: A Before-After Clinical Trial. J Reprod Infertil, 2025
- Predictive Value of Basal Serum Progesterone for Successful IVF in Endometriosis Patients: The Need for a Personalized Approach. J Pers Med, 2022
- A Narrative Review Regarding Implication of Ovarian Endometriomas in Infertility. Life (Basel), 2025
- The influence of ovarian cyst type and size on ovarian reserve markers: implications for fertility counseling and preservation strategy. Front Endocrinol (Lausanne), 2025