Abstract

Immune thrombocytopenic purpura (ITP) has been linked to the COVID-19 vaccine series as a rare adverse event but has recently emerged in the literature as a sequela of natural COVID-19 infection. ITP is a diagnosis of exclusion where a diagnosis is made by having isolated thrombocytopenia (platelet count <100,000/μL) and no other identifiable etiology for the thrombocytopenia. We share the case of a young male without any history of hematological or immunological disorders presenting with severe, symptomatic thrombocytopenia following a natural COVID-19 infection. Patients should be made aware of the potential risk of adverse events with not only vaccination but also even mild cases of natural infection with COVID-19. An emphasis should be placed on the fact that the benefits of vaccination continue to outweigh the potential risks of adverse events, even in those with a pre-existing diagnosis of ITP.

MeSH

Vaccines, Vaccination, Drug-Related Side Effects And Adverse Reactions, Covid-19, Diagnosis, Purpura, Thrombocytopenic, Purpura, Thrombocytopenia, Infections, Purpura, Thrombocytopenic, Idiopathic

Cited by

• ACVIM consensus statement on the diagnosis of immune thrombocytopenia in dogs and cats. J Vet Intern Med, 2024
• A Review of Hematological Complications and Treatment in COVID-19. Hematol Rep, 2023
• Immune Thrombocytopenia Purpura Associated With COVID-19 Infection: A Challenging Diagnosis and Management. Cureus, 2023
• Autoimmune Diseases Affecting Hemostasis: A Narrative Review. Int J Mol Sci, 2022