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Publications

Journal Article Review Epublish 2 citations

PubMed: 36120218 DOI: 10.7759/cureus.27926

The Use of Cannabis and Its Effects on Postpartum Depression.

Cureus 14(8):e27926

Authors: Oghenetega E Ayisire, Okelue E Okobi, Ngozi J Adaralegbe, Adeyemi A Adeosun, Divyaanshi Sood, Nkemputaife P Onyechi, Ogochukwu Agazie, Hameed O Shittu, Zainab Akinsola, Chukwudike G Nnaji, Oluwasayo J Owolabi, Nneka J Umeh, Imolikhe C Imobighe, Adewale M Adedoyin, Madinah Usman

Affiliations

  • Psychiatry, University of South Wales, Pontypridd, GBR.
  • Family Medicine, Lakeside Medical Center, Belle Glade, USA.
  • Allied Health Sciences, University of Connecticut, Waterbury, USA.
  • Molecular Pharmacology and Experiment Therapeutics, Mayo Clinic, Rochester, USA.
  • Oncology, Dayanand Medical College and Hospital, Ludhiana, IND.
  • Internal Medicine, University Hospitals Cleveland Medical Center, Cleveland, USA.
  • General Physician, College of Medicine University of Lagos, Idi Araba, NGA.
  • Internal Medicine, Federal Medical Centre, Abeokuta, NGA.
  • Internal Medicine/Family Medicine, Windsor University School of Medicine, Toronto, CAN.
  • Internal Medicine/Family Medicine, Windsor University School of Medicine, Chicago, USA.
  • Psychiatry, Lugansk Sate Medical University, Lugansk, UKR.
  • General Medicine, Brooklyn Queens Nursing Home, New York City, USA.
  • Obstetrics and Gynecology, Irrua Specialist Teaching Hospital, Irrua, NGA.
  • Internal Medicine, Lagos State University Teaching Hospital, Ikeja, NGA.
  • Medicine, Kharkiv National Medical University, Kharkiv, UKR.

Abstract

Cannabis use and depression management have been studied, with a preponderance of exacerbating effects, but there are few studies on postpartum depression (PPD). Depression affects a significant number of women, with a portion of it manifesting as PPD in childbearing women in the United States each year. The pharmacologic management approaches have disadvantages such as side effects, cost-benefit ratio, contraindications, use reluctance, medication adherence, and stigmatization in patients. Anecdotal claims of medical cannabis' therapeutic benefits have led to widespread legalization in several regions, making cannabis and its extracts a possible alternative. Cannabis is widely used during pregnancy and in general. Even though substance use disorders exacerbating depression symptoms have been reported, there are increasing reports and evidence about the therapeutic benefit of dose-dependent cannabis or its extracts in some depression symptoms, such as acute psychosocial stress relief, its purported anxiolytic effect, appetite, and sleep quality, thus stimulating more interest that may be inferred to depression. PPD marijuana use is unclear. This paper reviewed works of literature that claimed cannabis' therapeutic benefit in treating depression and, by extension, PPD. Our findings show the link between cannabis and PPD has not been fully explored. Self-reported studies link marijuana uses to positive mood, anxiety relief, sleep regulation, nausea and vomiting reduction, and appetite stimulation-all PPD symptoms. Others opposed postpartum marijuana use.

MeSH

Depression, Marijuana Use, Sleep, Signs And Symptoms, Appetite, Therapeutics, Depression, Postpartum, Postpartum Period

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