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Publications

Journal Article Review Epublish 16 citations

PubMed: 36233687 DOI: 10.3390/jcm11195822

The Effects of Race on Acute Kidney Injury.

J Clin Med 11(19)

Authors: Muzamil Olamide Hassan, Rasheed Abiodun Balogun

Affiliations

  • Department of Medicine, Obafemi Awolowo University, Ile-Ife 220005, Nigeria.
  • Division of Nephrology, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa.
  • Division of Nephrology, Department of Medicine, University of Virginia, Charlottesville, VA 22908, USA.

Abstract

Racial disparities in incidence and outcomes of acute kidney injury (AKI) are pervasive and are driven in part by social inequities and other factors. It is well-documented that Black patients face higher risk of AKI and seemingly have a survival advantage compared to White counterparts. Various explanations have been advanced and suggested to account for this, including differences in susceptibility to kidney injury, severity of illness, and socioeconomic factors. In this review, we try to understand and further explore the link between race and AKI using the incidence, diagnosis, and management of AKI to illustrate how race is directly related to AKI outcomes, with a focus on Black and White individuals with AKI. In particular, we explore the effect of race-adjusted estimated glomerular filtration rate (eGFR) equation on AKI prediction and discuss racial disparities in the management of AKI and how this might contribute to racial differences in AKI-related mortality among Blacks with AKI. We also identify some opportunities for future research and advocacy.

MeSH

Incidence, Acute Kidney Injury

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