Journal Article Review Epublish 66 citations
PubMed: 36838343 DOI: 10.3390/microorganisms11020378
Biosynthesis of Metal and Metal Oxide Nanoparticles Using Microbial Cultures: Mechanisms, Antimicrobial Activity and Applications to Cultural Heritage.
Microorganisms 11(2)
Authors: António Carrapiço, Maria Rosário Martins, Ana Teresa Caldeira, José Mirão, Luís Dias
Affiliations
- HERCULES Laboratory, Cultural Heritage, Studies and Safeguard, University of Évora, 7000-809 Évora, Portugal. Institute for Research and Advanced Training (IIFA), University of Évora, 7000-809 Évora, Portugal.
- HERCULES Laboratory, Cultural Heritage, Studies and Safeguard, University of Évora, 7000-809 Évora, Portugal.
- Department of Medicinal Sciences and Health, School of Health and Human Development, University of Évora, 7000-671 Évora, Portugal.
- Department of Chemistry and Biochemistry, School of Sciences and Technology, University of Évora, 7000-671 Évora, Portugal.
- Department of Geosciences, School of Sciences and Technology, University of Évora, 7000-671 Évora, Portugal.
- HERCULES Laboratory, Cultural Heritage, Studies and Safeguard, University of Évora, 7000-809 Évora, Portugal. Department of Geosciences, School of Sciences and Technology, University of Évora, 7000-671 Évora, Portugal.
Abstract
Nanoparticles (1 to 100 nm) have unique physical and chemical properties, which makes them suitable for application in a vast range of scientific and technological fields. In particular, metal nanoparticle (MNPs) research has been showing promising antimicrobial activities, paving the way for new applications. However, despite some research into their antimicrobial potential, the antimicrobial mechanisms are still not well determined. Nanoparticles' biosynthesis, using plant extracts or microorganisms, has shown promising results as green alternatives to chemical synthesis; however, the knowledge regarding the mechanisms behind it is neither abundant nor consensual. In this review, findings from studies on the antimicrobial and biosynthesis mechanisms of MNPs were compiled and evidence-based mechanisms proposed. The first revealed the importance of enzymatic disturbance by internalized metal ions, while the second illustrated the role of reducing and negatively charged molecules. Additionally, the main results from recent studies (2018-2022) on the biosynthesis of MNPs using microorganisms were summarized and analyzed, evidencing a prevalence of research on silver nanoparticles synthesized using bacteria aiming toward testing their antimicrobial potential. Finally, a synopsis of studies on MNPs applied to cultural heritage materials showed potential for their future use in preservation.
MeSH
Nanoparticles, Metal Nanoparticles, Research, Nanotechnology
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