Publications

Journal Article Review Research Support, Non-U.S. Gov't Ppublish 19 citations

PubMed: 37789715 DOI: 10.1111/jvh.13891

The elimination of hepatitis D as a public health problem: Needs and challenges.

J Viral Hepat 31(1):47-50

Authors: Thomas Vanwolleghem, Paige A Armstrong, Maria Buti, David FitzSimons, Sara Valckx, Greet Hendrickx, Pierre Van Damme

Affiliations

  • Laboratory for Experimental Medicine and Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
  • Universitair Ziekenhuis Antwerpen, Edegem, Belgium.
  • Viral Hepatitis Prevention Board, Centre for the Evaluation of Vaccination (CEV), VAXINFECTIO, University of Antwerp, Antwerp, Belgium.
  • Division of Viral Hepatitis, US Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA.
  • Hospital General Universitari Valle Hebron, Barcelona, Spain.
  • Independent Researcher, London, UK.

Abstract

Infection with hepatitis D virus leads to liver disease and cancer most rapidly of all hepatitis viruses. However, knowledge about hepatitis D remains poor and the burden and impact are underestimated, even though some 12-15 million people mainly in low- and middle-income countries may be affected. Its epidemiology is changing, with increasing migration leading to increased risks of infection and disease. A recent Viral Hepatitis Prevention Board meeting reviewed the current epidemiological status, improvements in diagnostic testing, advances in the development of novel antiviral agents in phase III trials and the need for a greater public health response, such as new guidelines and recommended testing of all people newly identified as infected with hepatitis B virus for hepatitis D virus infection. It identified issues and needs for attention with regard to prevention, diagnosis and treatment.

MeSH

Research Design, Hepatitis D, Epidemiology, Public Health, Viruses, Diagnosis, Therapeutics, Hepatitis, Viral, Human, Antiviral Agents, Infections, Hepatitis

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