Journal Article Epublish 1 citation
PubMed: 38167002 DOI: 10.1186/s13104-023-06661-z
Proteome dataset of Candida albicans (ATCC10231) opaque cell.
BMC Res Notes 17(1):2
Authors: Gajanan Zore, Mazen Abdulghani, Santosh Kodgire, Rubina Kazi, Amruta Shelar, Rajendra Patil
Affiliations
- Dept. of Biotechnology, School of Life Sciences, Central University of Rajasthan, Ajmer, Bandersindri NH 8, Kishangarh Dist Ajmer (Rajasthan), India.
- School of Life Sciences, Swami Ramanand Teerth Marathwada University, Nanded, 431606, MS, India.
- School of Life Sciences, Swami Ramanand Teerth Marathwada University, Nanded, 431606, MS, India.
- Division of Biochemical Sciences, CSIR-NCL, Pune-8, Pune, MS, India.
- Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind, Pune, 411007, MS, India.
Abstract
OBJECTIVES
Candida albicans, a polymorphic yeast, is one of the most common, opportunistic fungal pathogens of humans. Among the different morphological forms, opaque form is one of the least-studied ones. This opaque phenotype is essential for mating and is also reported to be involved in colonizing the gastrointestinal tract. Considering the significance of the clinical and sexual reproduction of C. albicans, we have investigated the morphophysiological modulations in opaque form using a proteomic approach.
DATA DESCRIPTION
In the current investigation, we have used Micro-Liquid Chromatography-Mass Spectrometry (LC-MS/MS) analysis to create a protein profile for opaque-specific proteins. Whole-cell proteins from C. albicans (ATCC10231) cells that had been cultured for seven days on synthetic complete dextrose (SCD) medium in both as an opaque (test) and as a white (control) form cells were extracted, digested, and identified using LC-MS/MS. This information is meant to serve the scientific community and represents the proteome profile (SWATH Spectral Libraries) of C. albicans opaque form.
MeSH
Cells, Biomedical Research, Candida Albicans, Proteome, Liquid Chromatography-Mass Spectrometry