Journal Article Review Epublish 7 citations
PubMed: 38337523 DOI: 10.3390/jcm13030831
Exploring the Impact of Glycemic Control on Diabetic Retinopathy: Emerging Models and Prognostic Implications.
J Clin Med 13(3)
Authors: Nicola Tecce, Gilda Cennamo, Michele Rinaldi, Ciro Costagliola, Annamaria Colao
Affiliations
- Unit of Endocrinology, Dipartimento di Medicina Clinica e Chirurgia, Federico II University Medical School of Naples, 80131 Napoli, Italy.
- Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples "Federico II", 80131 Naples, Italy.
- Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University, 80131 Naples, Italy.
Abstract
This review addresses the complexities of type 1 diabetes (T1D) and its associated complications, with a particular focus on diabetic retinopathy (DR). This review outlines the progression from non-proliferative to proliferative diabetic retinopathy and diabetic macular edema, highlighting the role of dysglycemia in the pathogenesis of these conditions. A significant portion of this review is devoted to technological advances in diabetes management, particularly the use of hybrid closed-loop systems (HCLSs) and to the potential of open-source HCLSs, which could be easily adapted to different patients' needs using big data analytics and machine learning. Personalized HCLS algorithms that integrate factors such as patient lifestyle, dietary habits, and hormonal variations are highlighted as critical to reducing the incidence of diabetes-related complications and improving patient outcomes.
MeSH
Diabetes Mellitus, Epidemiology, Machine Learning, Precision Medicine, Diabetes Complications, Diabetic Retinopathy, Glycemic Control
Cited by
- Vitamin D Deficiency as a Risk Factor for Diabetic Retinopathy: A Systematic Review and Meta-Analysis. Biomedicines, 2025
- Association Between HbA1c Levels and the Severity of Diabetic Retinopathy. Cureus, 2025
- Diabetic Retinopathy and Periodontitis: Implications from a Systematic Review and Meta-Analysis. Int Dent J, 2025
- The Hippo signalling pathway and its impact on eye diseases. J Cell Mol Med, 2024
- The Impact of Dyslipidemia on the Clinical Profile of Patients With Uncontrolled Diabetes. In Vivo, 2025
- Hybrid closed loop devices: The utility of continuous glucose monitoring metrics for retinal surveillance during transition from standard insulin pump. Eye (Lond), 2025
- Hybrid closed loop and intensive insulin delivery technology: Reviewing the effect of improving 'time in range' glucose levels on diabetic retinopathy. Eye (Lond), 2025