Preprint Epublish 99 citations
PubMed: 38410648
ITRUSST Consensus on Standardised Reporting for Transcranial Ultrasound Stimulation.
ArXiv
Authors: Eleanor Martin, Jean-François Aubry, Mark Schafer, Lennart Verhagen, Bradley Treeby, Kim Butts Pauly
Affiliations
- Department of Medical Physics and Biomedical Engineering, University College London, London, U.K.
- Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.
- Physics for Medicine Paris, Inserm U1273, ESPCI Paris, CNRS UMR8063, PSL University, Paris, France.
- School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA USA.
- Donders Institute for Brain, Cognition and Behaviour, Radboud University, 6525 GD Nijmegen, the Netherlands.
- Department of Radiology, Stanford University, Stanford, CA, USA.
Abstract
As transcranial ultrasound stimulation (TUS) advances as a precise, non-invasive neuromodulatory method, there is a need for consistent reporting standards to enable comparison and reproducibility across studies. To this end, the International Transcranial Ultrasonic Stimulation Safety and Standards Consortium (ITRUSST) formed a subcommittee of experts across several domains to review and suggest standardised reporting parameters for low intensity TUS, resulting in the guide presented here. The scope of the guide is limited to reporting the ultrasound aspects of a study. The guide and supplementary material provide a simple checklist covering the reporting of: (1) the transducer and drive system, (2) the drive system settings, (3) the free field acoustic parameters, (4) the pulse timing parameters, (5) estimates of exposure parameters in the brain, and (6) intensity parameters. Detailed explanations for each of the parameters, including discussions on assumptions, measurements, and calculations, are also provided.