Journal Article Review Epublish 5 citations
PubMed: 38421529 DOI: 10.1007/s10142-024-01325-y
Harnessing the potential of mutation breeding, CRISPR genome editing, and beyond for sustainable agriculture.
Funct Integr Genomics 24(2):44
Authors: Nelissa Maisara Nor A'azizam, Sakshi Chopra, Praveen Guleria, Vineet Kumar, Muhamad Hafiz Abd Rahim, Jamilah Syafawati Yaacob
Affiliations
- Institute of Biological Sciences, Faculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
- Plant Biotechnology and Genetic Engineering Lab, Department of Biotechnology, DAV University, Jalandhar, Punjab, 144012, India.
- Department of Biotechnology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab, 144111, India.
- Department of Food Science, Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.
- Institute of Biological Sciences, Faculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
- Centre for Research in Biotechnology for Agriculture (CEBAR), Faculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Abstract
By 2050, the global population is projected to exceed 9.5 billion, posing a formidable challenge to ensure food security worldwide. To address this pressing issue, mutation breeding in horticultural crops, utilizing physical or chemical methods, has emerged as a promising biotechnological strategy. However, the efficacy of these mutagens can be influenced by various factors, including biological and environmental variables, as well as targeted plant materials. This review highlights the global challenges related to food security and explores the potential of mutation breeding as an indispensable biotechnological tool in overcoming food insecurity. This review also covers the emergence of CRISPR-Cas9, a breakthrough technology offering precise genome editing for the development of high-yield, stress-tolerant crops. Together, mutation breeding and CRISPR can potentially address future food demands. This review focuses into these biotechnological advancements, emphasizing their combined potential to fortify global food security in the face of a booming population.
MeSH
Clustered Regularly Interspaced Short Palindromic Repeats, Food, Mutation, Breeding, Genome, Agriculture, Gene Editing