Publications

Journal Article Review Epublish 1 citation

PubMed: 38487050 DOI: 10.1016/j.cjco.2023.11.019

Gender-Related Factors Associated With Outcomes of Acute Coronary Syndrome in Young Female Patients.

CJC Open 6(2Part B):370-379

Authors: Adriana Angarita-Fonseca, Alexandra Peebles, Louise Pilote

Affiliations

  • Research Institute of the McGill University Health Centre and Department of Medicine, McGill University, Montreal, Quebec, Canada.

Abstract

Acute coronary syndrome (ACS) remains a significant global health concern, with a growing recognition of its impact on young adults, particularly young female adults. Although gender-related factors, defined as a social construct that encompasses 4 distinct dimensions (gender roles, gender identity, gender relations, and institutionalized gender) are undoubtedly relevant across age groups, young female patients with ACS face specific challenges and disparities in outcomes, compared to other populations. This narrative review examines the role of gender-related factors-specifically, gender roles, gender identity, gender relations, and institutionalized gender-in influencing objective and subjective ACS outcomes in young female patients. In the 5 articles identified, the objective outcomes included hospital readmission, "door-to-electrocardiography" time, and coronary atherosclerosis progression. Subjective outcomes, such as physical and mental functional status, quality of life, physical limitations, and vital exhaustion, were also examined. Being employed, which is a gender role, emerged as a protective factor against hospital readmission. Gender identity factors such as depression and stress were correlated with negative outcomes, and anxiety influenced "door-to-electrocardiography" times. Institutional factors, including income disparities, affected readmission likelihood. Strong social support decreased physical limitations post-ACS, whereas financial challenges and lower education negatively impacted quality of life and vital exhaustion. These findings underscore the intricate interplay of gender dimensions in shaping ACS outcomes among young female patients. Integrating these insights into clinical practice and research can enhance care, mitigate disparities, and foster improved cardiovascular health in this vulnerable population.

MeSH

Quality Of Life, Acute Coronary Syndrome, Gender Role, Gender Identity, Electrocardiography