System Maintenance Notice

Please note that maintenance work is scheduled between 4 AM and 5 AM - CET. During this time, you may experience reduced performance. Thanks for your patience.

Publications

Journal Article Review Epublish 30 citations

PubMed: 38543512 DOI: 10.3390/microorganisms12030461

: A Mysterious Member of the Gut Microbiome.

Microorganisms 12(3)

Authors: Mehmet Aykur, Erdoğan Malatyalı, Filiz Demirel, Burçak Cömert-Koçak, Eleni Gentekaki, Anastasios D Tsaousis, Funda Dogruman-Al

Affiliations

  • Department of Parasitology, Faculty of Medicine, Tokat Gaziosmanpasa University, Tokat 60030, Türkiye.
  • Department of Parasitology, Faculty of Medicine, Aydin Adnan Menderes University, Aydin 09010, Türkiye.
  • Department of Medical Microbiology, Ankara City Hospital, Health Science University, Ankara 06500, Türkiye.
  • Department of Medical Microbiology, Karadeniz Ereğli State Hospital, Zonguldak 67300, Türkiye.
  • Department of Veterinary Medicine, School of Veterinary Medicine, University of Nicosia, Nicosia 2414, Cyprus.
  • Laboratory of Molecular and Evolutionary Parasitology, RAPID Group, School of Biosciences, University of Kent, Canterbury CT2 7NZ, UK.
  • Division of Medical Parasitology, Department of Medical Microbiology, Faculty of Medicine, Gazi University, Ankara 06560, Türkiye.

Abstract

is the most common gastrointestinal protist found in humans and animals. Although the clinical significance of remains unclear, the organism is increasingly being viewed as a commensal member of the gut microbiome. However, its impact on the microbiome is still being debated. It is unclear whether promotes a healthy gut and microbiome directly or whether it is more likely to colonize and persist in a healthy gut environment. In healthy people, is frequently associated with increased bacterial diversity and significant differences in the gut microbiome. Based on current knowledge, it is not possible to determine whether differences in the gut microbiome are the cause or result of colonization. Although it is possible that some aspects of this eukaryote's role in the intestinal microbiome remain unknown and that its effects vary, possibly due to subtype and intra-subtype variations and immune modulation, more research is needed to characterize these mechanisms in greater detail. This review covers recent findings on the effects of in the gut microbiome and immune modulation, its impact on the microbiome in autoimmune diseases, whether has a role like bacteria in the gut-brain axis, and its relationship with probiotics.

MeSH

Autoimmune Diseases, Bacteria, Probiotics, Gastrointestinal Microbiome

Cited by