Journal Article Research Support, Non-U.S. Gov't Ppublish
PubMed: 38813652 DOI: 10.1080/21645515.2024.2355037
Decoding trends in mRNA vaccine research: A comprehensive bibliometric study.
Hum Vaccin Immunother 20(1):2355037
Authors: Chaobin Zhang, Yuhang Wang, Jianding Peng, Xiaotian Wen, Youwen Zhang, Kejun Li, Hanjian Du, Xiaofei Hu
Affiliations
- Southwest Eye Hospital, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.
- School of Basic Medicine, Capital Medical University, Beijing, China.
- School of Law, City University of Hongkong, Hong Kong, China.
- Department of Library, Chongqing Vocational Institute of Engineering, Chongqing, China.
- Department of Neurosurgery, Chongqing Research Center for Glioma Precision Medicine, Chongqing General Hospital, Chongqing University, Chongqing, China.
- Department of Nuclear Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.
Abstract
BACKGROUND
In recent years, infectious diseases like COVID-19 have had profound global socio-economic impacts. mRNA vaccines have gained prominence due to their rapid development, industrial adaptability, simplicity, and responsiveness to new variants. Notably, the 2023 Nobel Prize in Physiology or Medicine recognized significant contributions to mRNA vaccine research.
METHODS
Our study employed a comprehensive bibliometric analysis using the Web of Science Core Collection (WoSCC) database, encompassing 5,512 papers on mRNA vaccines from 2003 to 2023. We generated cooperation maps, co-citation analyses, and keyword clustering to evaluate the field's developmental history and achievements.
RESULTS
The analysis yielded knowledge maps highlighting countries/institutions, influential authors, frequently published and highly cited journals, and seminal references. Ongoing research hotspots encompass immune responses, stability enhancement, applications in cancer prevention and treatment, and combating infectious diseases using mRNA technology.
CONCLUSIONS
mRNA vaccines represent a transformative development in infectious disease prevention. This study provides insights into the field's growth and identifies key research priorities, facilitating advancements in vaccine technology and addressing future challenges.
MeSH
Vaccines, Rna, Messenger, Bibliometrics, Research, Communicable Diseases