Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Ppublish
PubMed: 38816279 DOI: 10.1016/j.tibs.2024.05.005
Subconductance states add complexity to Piezo1 gating model.
Trends Biochem Sci 49(7):567-568
Authors: Marie E Cronin, Jörg Grandl
Affiliations
- Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA.
- Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA.
Abstract
Piezos are force-gated ion channels that detect and communicate membrane tension to the cell. Recent work from Ullah, Nosyreva, and colleagues characterizes partial channel openings, known as subconductance states, and develops a new gating model of Piezo1 function.
MeSH
Biochemistry