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Journal Article Journal Article Epublish 1 citation

PubMed: 39339830 DOI: 10.3390/v16091353

Long-Term SARS-CoV-2 Findings Related to Persisting Viral Antigen and Inflammation Resemble Those Reported for Influenza Virus and Respiratory Syncytial Virus.

Viruses 16(9)

Authors: Norbert J Roberts

Affiliations

  • Division of Infectious Diseases and Immunology, Department of Medicine, New York University Grossman School of Medicine, New York, NY 10016, USA.
  • Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA.

Abstract

Recent studies have documented prolonged expression of viral antigens and RNA and associated inflammation after infection with SARS-CoV-2 in a substantial proportion of infected patients. The persisting SARS-CoV-2 effects and findings, with inflammation associated with continued detection of viral antigens, especially resemble those previously reported for influenza virus, as well as respiratory syncytial virus (RSV). The reports indicate the need for improved insight into the mechanisms whereby post-SARS-CoV-2 infection-related illness is apparently more common and perhaps even more persistent after infection than observed for other respiratory viruses.

MeSH

Asthenia, Antigens, Viral, Respiratory Syncytial Viruses, Sars-Cov-2, Virology, Influenza, Human, Viruses, Severe Acute Respiratory Syndrome-Related Coronavirus, Orthomyxoviridae, Infections