Publications

Journal Article Review Ppublish 6 citations

PubMed: 39345043 DOI: 10.1080/17460913.2024.2401263

Air pollution, dysbiosis and diseases: pneumonia, asthma, COPD, lung cancer and irritable bowel syndrome.

Future Microbiol 19(17):1497-1513

Authors: Shelja Agarwal, Nandini Tomar, Meet Makwana, Sandeep Patra, Balu A Chopade, Vandana Gupta

Affiliations

  • Department of Microbiology, Ram Lal Anand College, University of Delhi, Benito Juarez Road, New Delhi, 110021, India.
  • AKS University, Satna, Madhya Pradesh, India.
  • Department of Microbiology, Savitribai Phule Pune University, Pune, 411007, Maharashtra, India.

Abstract

With substantial effects on human health, air pollution has become a major global concern. Air pollution has been linked to numerous gastrointestinal and respiratory diseases with increasing mortalities. The gut and respiratory dysbiosis brought about by air pollution has recently received much attention. This review attempts to provide an overview of the types of air pollutants, their sources, their impact on the respiratory and gut dysbiotic patterns and their correlation with five major diseases including pneumonia, asthma, COPD, lung cancer and irritable bowel syndrome. Deeper insights into the links between pollutants, dysbiosis and disease may pave the way for novel diagnostic biomarkers for prognosis and early detection of these diseases, as well as ways to ease the disease burden.

MeSH

Dysbiosis, Irritable Bowel Syndrome, Lung, Environmental Pollutants, Air Pollution, Neoplasms, Air, Pulmonary Disease, Chronic Obstructive, Lung Neoplasms, Pneumonia, Environmental Pollution, Asthma, Infections