Journal Article Review Ppublish
PubMed: 39357077 DOI: 10.1016/j.coi.2024.102483
Molecular mechanisms regulating T helper 2 cell differentiation and function.
Curr Opin Immunol 91:102483
Authors: Aydan Ch Szeto, Ana Cf Ferreira, Andrew Nj McKenzie
Affiliations
- MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom.
Abstract
T helper 2 (T H2) cells orchestrate type 2 immunity during protective antihelminth immunity and help restore tissue homoeostasis. Their misdirected activities against innocuous substances also underlie atopic diseases, such as asthma and allergy. Recent technological advances are uncovering novel insights into the molecular mechanisms governing T H2 cell differentiation and function.
MeSH
Cells, Cell Differentiation, Immunity, Th2 Cells