Journal Article Ppublish 2 citations
PubMed: 39397413 DOI: 10.5543/tkda.2024.63367
Baseline Characteristics and Clinical Insights from the ARTEMIS Registry: A Comprehensive Study of Peripartum Cardiomyopathy in Türkiye.
Turk Kardiyol Dern Ars 52(7):474-483
Authors: Meral Kayıkçıoğlu, Murat Biteker, Ferit Onur Mutluer, Tuncay Güzel, Emre Yılmaz, Emre Demir, Sanem Nalbantgil, Faruk Ertaş, Dilek Çiçek Yılmaz, Ahmet Temizhan, Lütfü Aşkın, Lale Dinç Asarcıklı, Murat Akçay, Recep Demirbağ, Sedat Köroğlu, Ender Örnek, Ahmet Çelik, Mehmet Ata Akıl, Bayram Arslan, Lale Tokgözoğlu
Affiliations
- Department of Cardiology, Ege University Faculty of Medicine, Izmir, Türkiye.
- Department of Cardiology, Muğlu University Faculty of Medicine, Muğla, Türkiye.
- Department of Cardiology, Yeditepe University Hospital, İstanbul, Türkiye.
- Department of Cardiology, Health Science University, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Türkiye.
- Department of Cardiology, Giresun University Faculty of Medicine, Giresun, Türkiye.
- Department of Cardiology, Dicle University, Diyarbakır, Türkiye.
- Department of Cardiology, Mersin University Faculty of Medicine, Mersin, Türkiye.
- Department of Cardiology, Ankara City Hospital, University of Health Sciences, Ankara, Türkiye.
- Department of Cardiology, Gaziantep Islamic Science and Technology University, Gaziantep, Türkiye.
- Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, İstanbul, Türkiye.
- Department of Cardiology, Ondokuz Mayis University Faculty of Medicine, Samsun, Türkiye.
- Department of Cardiology, Harran University, Şanlıurfa, Türkiye.
- Department of Cardiology, Afşin State Hospital, Kahramanmaraş, Türkiye.
- Department of Cardiology, Ergani State Hospital, Diyarbakır, Türkiye.
- Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
Abstract
OBJECTIVE
Peripartum Cardiomyopathy (PPCM) is a life-threatening, rare disorder that occurs during the late stages of pregnancy or the early postpartum period. The ARTEMIS (A RegisTry of pEripartuM cardIomyopathy in Turkish patientS) aims to investigate the clinical characteristics and outcomes of PPCM in Türkiye, providing insights into its management within this specific population.
METHODS
The ARTEMIS registry retrospectively enrolled patients diagnosed with PPCM within the last five years at 44 cardiology centers across Türkiye. Eligible participants were women over 18 years old, diagnosed with PPCM and without other known cardiac pathology. Data collected included demographic information, clinical presentation, diagnostic modalities, treatment regimens, and outcomes.
RESULTS
The study included 293 patients, predominantly between 25 and 35 years old. The majority presented with symptoms such as dyspnea and palpitations, diagnosed postpartum via echocardiography. A low use of advanced diagnostic imaging was noted, relying primarily on echocardiography for evaluation. Common treatments included beta blockers (97.8%), angiotensin-converting enzyme (ACE) inhibitors (71.3%), and in severe cases, bromocriptine (6.9%). The study highlighted a mortality rate of 5.1%, with surviving patients often requiring continued management for heart failure. Diagnostic challenges and variations in treatment responses were noted, reflecting the complexity of PPCM diagnosis and care.
CONCLUSION
The ARTEMIS registry provides valuable insights into the management of PPCM in Türkiye, highlighting the need for targeted educational programs for healthcare providers and patients. It also underscores the importance of national registries in understanding and improving outcomes for rare diseases like PPCM.
MeSH
Registries, Cardiovascular Diseases, Echocardiography, Therapeutics, Peripartum Period, Postpartum Period, Cardiomyopathies