Journal Article Review Research Support, Non-U.S. Gov't Ppublish
PubMed: 39403796 DOI: 10.1080/21505594.2024.2416551
Host combats porcine reproductive and respiratory syndrome virus infection at non-coding RNAs level.
Virulence 15(1):2416551
Authors: Zhi Qin, Weiye Liu, Zhihua Qin, Hongliang Zhang, Xuewei Huang
Affiliations
- College of Mechanical and Electrical Engineering, Qingdao Agricultural University, Qingdao, P.R. China.
- College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, P.R. China.
Abstract
Porcine reproductive and respiratory syndrome virus (PRRSV) poses a significant threat to the global swine industry. The emergence of new, highly virulent strains has precipitated recurrent outbreaks worldwide, underscoring the ongoing battle between host and virus. Thus, there is an imperative to formulate a more comprehensive and effective disease control strategy. Studies have shown that host non-coding RNA (ncRNA) is an important regulator of host - virus interactions in PRRSV infection. Hence, a thorough comprehension of the roles played by ncRNAs in PRRSV infection can augment our understanding of the pathogenic mechanisms underlying PRRSV infection. This review focuses on elucidating contemporary insights into the roles of host microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs) in PRRSV infection, providing both theoretical foundations and fresh perspectives for ongoing research into the mechanisms driving PRRSV infection and its pathogenesis.
MeSH
Porcine Reproductive And Respiratory Syndrome, Micrornas, Rna, Circular, Viruses, Porcine Respiratory And Reproductive Syndrome Virus, Virulence, Infections, Virus Diseases