System Maintenance Notice

Please note that maintenance work is scheduled between 4 AM and 5 AM - CET. During this time, you may experience reduced performance. Thanks for your patience.

Publications

Journal Article Review Ppublish 21 citations

PubMed: 39444390 DOI: 10.4103/jcecho.jcecho_37_24

Clinical Applications of Myocardial Work in Echocardiography: A Comprehensive Review.

J Cardiovasc Echogr 34(3):99-113

Authors: Giancarlo Trimarchi, Scipione Carerj, Gianluca Di Bella, Roberta Manganaro, Fausto Pizzino, Davide Restelli, Giuseppe Pelaggi, Francesca Lofrumento, Roberto Licordari, Giovanni Taverna, Umberto Paradossi, Cesare de Gregorio, Antonio Micari, Giovanna Di Giannuario, Concetta Zito

Affiliations

  • Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
  • Heart Centre, Cardiology Unit, Fondazione Gabriele Monasterio, Massa, Italy.
  • Department of Biomedical and Dental Sciences and of Morphological and Functional Images, University of Messina, Messina, Italy.
  • Department of Cardiology, Infermi Hospital, Rimini, Italy.

Abstract

Left ventricular (LV) global longitudinal strain (GLS) has recently garnered attention as a reliable and objective method for evaluating LV systolic function. One of the key advantages of GLS is its ability to detect subtle abnormalities even when the ejection fraction (EF) appears to be preserved. However, it is important to note that GLS, much like LVEF, is significantly influenced by load conditions. In recent years, researchers and clinicians have been exploring noninvasive myocardial work (MW) quantification as an innovative tool for assessing myocardial function. This method integrates measurements of strain and LV pressure, providing a comprehensive evaluation of the heart's performance. Notably, MW offers an advantage over GLS and LVEF because it provides a load-independent assessment of myocardial performance. The implementation of commercial echocardiographic software that facilitates the noninvasive calculation of MW has significantly broadened the scope of its application. This advanced technology is now being utilized in multiple clinical settings, including ischemic heart disease, valvular diseases, cardiomyopathies, cardio-oncology, and hypertension. One of the fundamental aspects of MW is its correlation with myocardial oxygen consumption, which allows for the assessment of work efficiency. Understanding this relationship is crucial for diagnosing and managing various cardiac conditions. The aim of this review is to provide an overview of the noninvasive assessment of myocardial by echocardiography, from basic principles and methodology to current clinical applications.

MeSH

Heart Failure, Heart, Work, Echocardiography

Cited by