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Publications

Journal Article Review Epublish

PubMed: 39552990 DOI: 10.7759/cureus.72808

Nanoparticle-Based Therapies for Cardiovascular Diseases: A Literature Review of Recent Advances and Clinical Potential.

Cureus 16(10):e72808

Authors: Gaurav Jha, Ritika B Sharma, Sruthi Sridhar, Disha Hayagreev, Tanya Sinha, Harsimran Kaur, Adrija Das, Reddy Lahari Bollineni

Affiliations

  • Trauma and Orthopaedics, Leicester Royal Infirmary, Leicester, GBR.
  • Geriatrics, Pinderfields General Hospital, MidYorkshire, GBR.
  • Emergency Department, Croydon Health Services NHS Trust, London, GBR.
  • Emergency Department, Basingstoke and North Hampshire Hospital, Basingstoke, GBR.
  • Emergency Medicine, South Tyneside and Sunderland NHS Foundation Trust, South Sheilds, GBR.
  • Accident and Emergency, Ealing Hospital, Southall, GBR.
  • Medicine, Newcastle University, Newcastle, GBR.
  • Internal Medicine, Royal Stoke Hospital, Stoke-on-Trent, GBR.

Abstract

Cardiovascular diseases (CVDs) present a significant global health burden and remain the leading cause of morbidity and mortality worldwide. Conventional pharmacological therapies have yielded limited success in addressing the underlying pathophysiology of these diseases, leading to the exploration of novel therapeutic approaches. Nanotechnology is transforming cardiovascular disease management by enabling the engineering of materials at the atomic and molecular levels. This has led to the development of advanced diagnostic tools with unparalleled accuracy and sensitivity in detecting these diseases. By enabling targeted drug delivery, enhancing imaging techniques, and facilitating personalized therapies, nanotechnology promises significant advancements in the diagnosis, treatment, and prevention of cardiovascular diseases. This narrative review provides a comprehensive outlook on the recent advancements in nanoparticle-based therapies for cardiovascular diseases. We delve into the diverse applications of various nanoparticle types, exploring their potential to surpass the limitations of conventional treatments and improve clinical outcomes. Additionally, we critically examine the challenges and future directions of this rapidly evolving field, emphasizing the need for rigorous clinical evaluation.

MeSH

Nanoparticles, Cardiovascular Diseases, Therapeutics