Case Reports Journal Article Epublish 1 citation
PubMed: 39822441 DOI: 10.7759/cureus.75887
Creutzfeldt-Jakob Disease in a Saudi Female: A Case Report.
Cureus 16(12):e75887
Authors: Fahad Albadr, Saba M Aldusaymani, Yousef A Aldobikhi, Sanad I Alkhaldi, Hatim S Sendy, Hamdan S Aldosari, Abdulaziz S Aljurayyad
Affiliations
- Radiology and Medical Imaging, King Saud Medical City, Riyadh, SAU.
- Neuroradiology, King Saud University, Riyadh, SAU.
- Medicine, AlMaarefa University, Riyadh, SAU.
- Department of Diagnostic Radiology, King Khalid University Hospital, Riyadh, SAU.
- Medicine, Northern Border University, Arar, SAU.
- Medicine, Imam Mohammed Ibn Saud University, Riyadh, SAU.
- Medicine, King Saud University Medical School, Riyadh, SAU.
Abstract
Creutzfeldt-Jakob disease (CJD) is a rare, rapidly progressive, and incurable neurodegenerative disorder caused by prions. It is invariably fatal and classified under transmissible spongiform encephalopathies. This case report presents a 66-year-old Saudi female who was admitted to the neurology department due to a rapidly advancing cognitive decline. The patient underwent diagnostic evaluation, including magnetic resonance imaging (MRI) and electroencephalogram (EEG). Following a month of hospitalization with psychosocial support, the patient was stable and subsequently discharged. In conclusion, while CJD is an uncommon condition, it should be considered in the differential diagnosis of patients presenting with rapidly progressive dementia. Early and accurate diagnosis is essential to differentiate this untreatable disease from other treatable forms of rapidly progressive dementia and to facilitate potential future therapeutic interventions.
MeSH
Dementia, Creutzfeldt-Jakob Syndrome, Diagnosis, Neurodegenerative Diseases