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Journal Article Ppublish 2 citations

PubMed: 39871665 DOI: 10.1111/joor.13945

Oral Dysaesthetic and Perceptual Disorder, A Distinct Subset of Chronic Orofacial Pain Without Burning Symptoms: A Case-Control Study.

J Oral Rehabil 52(5):651-666

Authors: Gennaro Musella, Federica Canfora, Vito Carlo Alberto Caponio, Emmanouil Vardas, Maria Kouri, Nikolaos Nikitakis, Giuseppe Troiano, Massimo Aria, Luca D'Aniello, Lorenzo Lo Muzio, Michele Davide Mignogna, Daniela Adamo

Affiliations

  • Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
  • Department of Neuroscience, Reproductive Sciences, and Dentistry, University of Naples Federico II, Naples, Italy.
  • Department of Oral Medicine and Pathology and Hospital Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
  • Department of Economics and Statistics, University of Naples Federico II, Naples, Italy.
  • Department of Social Sciences, University of Naples Federico II, Naples, Italy.
  • Department of Life Science, Health, and Health Professions, Link Campus University, Rome, Italy.

Abstract

BACKGROUND

According to the ICOP 2020, Burning Mouth Syndrome (BMS) is a chronic orofacial pain disorder characterised by an intraoral burning sensation, which represents the main diagnostic criterion. However, some patients experience other symptoms such as xerostomia, taste alterations, and globus, without the burning sensation (non-BMS).

OBJECTIVE

This study aims to explore non-BMS as a distinct subclinical entity by comparing the classical BMS with this new group of patients in a case-control study, addressing gaps in current diagnostic criteria.

METHODS

Eighty-three non-BMS patients were compared with an equal number of BMS patients matched for age and sex. Data on sociodemographic and risk factors, systemic comorbidities and drug intake, symptom patterns, psychological profiles were collected and statistically analysed.

RESULTS

No significant differences between BMS and non-BMS groups were found in sociodemographic characteristics, comorbidities, drug consumption and extraoral symptoms. Both groups reported similar symptoms patterns, with discomfort intensifying in the evening. Although oral symptoms prevalence varied, with the burning sensation exclusive to BMS patients, none of these differences reached statistical significance. Psychological assessments revealed mild depression (17 [14-19] vs. 17 [14-20], p  0.981), mild to moderate anxiety (18 [15-21] vs. 17 [15-20.5], p = 0.767), and sleep disturbance (5 [4-7] vs. 8 [5-10], p < 0.001) in both groups.

CONCLUSION

Non-BMS patients exhibit similarities to BMS patients yet remain unclassified under current diagnostic criteria. Therefore, we have suggested the term "Oral Dysaesthetic and Perceptual Disorder (ODPD)" to define these patients (non-BMS). This study emphasises the need to expand diagnostic criteria to better identify and manage ODPD patients.

MeSH

Comorbidity, Mouth Rehabilitation, Dysgeusia, Perceptual Disorders, Pain, Pharmaceutical Preparations, Case-Control Studies, Sensation, Dentures, Signs And Symptoms, Dental Materials