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Publications

Journal Article Review Epublish 1 citation

PubMed: 39941205 DOI: 10.3390/diagnostics15030275

Recognition of Idiopathic Inflammatory Myopathies Underlying Interstitial Lung Diseases.

Diagnostics (Basel) 15(3)

Authors: Giulia Morina, Domenico Sambataro, Alessandro Libra, Stefano Palmucci, Michele Colaci, Gaetano La Rocca, Francesco Ferro, Linda Carli, Chiara Baldini, Santa Valentina Liuzzo, Carlo Vancheri, Gianluca Sambataro

Affiliations

  • Department of Clinical and Experimental Medicine, Regional Referral Center for Rare Lung Diseases, Policlinico "G.Rodolico-San Marco", University of Catania, 95123 Catania, Italy.
  • Artroreuma S.R.L. Outpatient Clinic Associated with the Regional Health System, Mascalucia, 95030 Catania, Italy.
  • Unità Operativa Semplice Dipartimentale di Imaging Polmonare e Tecniche Radiologiche Avanzate (UOSD IPTRA), Department of Medical Surgical Sciences and Advanced Technologies "GF Ingrassia", University Hospital Policlinico "G.Rodolico-San Marco", University of Catania, 95123 Catania, Italy.
  • Internal Medicine Unit, Division of Rheumatology, Department of Clinical and Experimental Medicine, Cannizzaro Hospital, University of Catania, 95123 Catania, Italy.
  • Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
  • Department of Medicine and Surgery, University of Enna "Kore", 94100 Enna, Italy.

Abstract

Interstitial Lung Disease (ILD) is one of the most common causes of mortality in idiopathic Inflammatory Myopathies (IIM). Despite these conditions being commonly associated with proximal weakness, skin rashes and arthritis, ILD can be the first or the sole clinical feature in up to 60% of patients, potentially leading to incorrect diagnosis. The early recognition of an underlying IIM in ILD patients can allow for prompt treatment, which could potentially stabilize or even improve the lung disease, also avoiding the development of other clinical features associated with the condition. The objective of this review is to describe the clinical, serological and radiological features associated with IIM-ILD, mainly focusing on dermatomyositis and antisynthetase syndrome.

MeSH

Dermatomyositis, Muscular Diseases, Autoantibodies, Lung, Myositis, Polymyositis, Lung Diseases, Lung Diseases, Interstitial

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