Journal Article Epublish 2 citations
PubMed: 39958979 DOI: 10.1515/med-2025-1144
The era of increasing cancer survivorship: Trends in fertility preservation, medico-legal implications, and ethical challenges.
Open Med (Wars) 20(1):20251144
Authors: Lina De Paola, Gabriele Napoletano, Giuseppe Gullo, Francesco Circosta, Gianluca Montanari Vergallo, Susanna Marinelli
Affiliations
- Department of Anatomical, Histological, Forensic and Orthopedic Sciences, Sapienza University of Rome, Rome, Italy.
- Department of Obstetrics and Gynecology, Villa Sofia Cervello Hospital, University of Palermo, Palermo, 90146, Italy.
- Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, "Sapienza" University of Rome, Rome, Italy.
- School of Law, Polytechnic University of Marche, 60121, Ancona, Italy.
Abstract
Introduction
Global cancer cases are increasing, but fortunately, cancer is becoming more treatable. By 2050, the number of cancer cases is projected to reach 35 million. These numbers are certainly correlated with the aging population, early diagnoses due to screenings, and the broad current treatment options. However, life-saving therapies are often gonadotoxic, significantly impacting the lives of cancer patients. Fertility preservation following life-saving oncological treatments is one of the challenges faced by patients with cancer.
Material and method
We analyzed 73 articles to investigate the current state of fertility preservation in oncology, also evaluating the medico-legal implications.
Results
The data indicate a growing trend of cancer recoveries and survivorship with opportunities to access fertility preservation through various methods, which are not entirely known or consistently offered to patients in the appropriate manner.
Conclusions
The ethical and medico-legal aspects are numerous and seem to be still evolving.
MeSH
Fertility, Fertility Preservation, Neoplasms, Survivorship, Therapeutics
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