Journal Article Research Support, Non-U.S. Gov't Epublish
PubMed: 40017622 DOI: 10.1155/carj/4709567
The Relationship Between Air Pollution, Meteorological Factors, and Eosinophil Counts in Peripheral Blood of Patients With Allergic Rhinitis: A Cross-Sectional Study.
Can Respir J 2025:4709567
Authors: Boya Fan, Gang Wang, Lei Wang, Wei Wu
Affiliations
- Department of Otolaryngology Head and Neck Surgery, The Ninth Medical Center of PLA General Hospital, Beijing 100101, China. Department of Otolaryngology Head and Neck Surgery, Peking University Third Hospital, Beijing 100191, China. State Environmental Protection Key Laboratory of Environmental Sense Organ Stress and Health, Beijing 100101, China.
- Department of Otolaryngology Head and Neck Surgery, The Ninth Medical Center of PLA General Hospital, Beijing 100101, China. State Environmental Protection Key Laboratory of Environmental Sense Organ Stress and Health, Beijing 100101, China.
Abstract
To evaluate the relationship between air pollution, meteorological factors, and eosinophils in the peripheral blood of allergic rhinitis (AR) patients. We conducted a retrospective study of medical records from the Ninth Medical Center of PLA General Hospital in Beijing. A review of medical records (1 January 2014-31 August 2022) of 1080 AR patients who underwent peripheral blood eosinophil count tests. Patients were stratified into elevated and normal eosinophil count groups. Daily meteorological data (mean temperature and relative humidity) and ambient pollutant levels (PM2.5, PM10, NO, SO, CO, and ozone [O]) were collected. The mean pollutant levels and meteorological factors on the day of eosinophil count measurement were calculated separately for each group. Linear regression was performed to analyze the association between eosinophil counts and both meteorological factors and pollutant levels among AR patients. In 1080 AR patients, 11.85% had elevated eosinophil counts. Higher temperature (16.88 ± 9.09°C), humidity (57.75 ± 17.22%), and O levels (116.54 ± 54.92 μg/m) correlated significantly ( < 0.05) with elevated eosinophil counts. Linear regression confirmed positive associations between eosinophil count and temperature ( = 0.003), humidity ( = 0.001), and O ( = 0.0004) ( < 0.05). Other pollutants showed no significant differences. Elevated eosinophil counts in AR patients correlated significantly with higher temperature, humidity, and O levels. Linear regression confirmed positive associations between eosinophil count and these meteorological factors.
MeSH
Cross-Sectional Studies, Blood, Environmental Pollutants, Rhinitis, Allergic, Air Pollution, Humidity, Eosinophils, Air, Environmental Pollution, Records, Rhinitis, Temperature, Medical Records