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Publications

Journal Article Ppublish

PubMed: 40327605 DOI: 10.1158/0008-5472.CAN-24-2938

Combining Multiplexed CRISPR/Cas9-Nickase and PARP Inhibitors Efficiently and Precisely Targets Cancer Cells.

Cancer Res 85(15):2890-2904

Authors: Soyoung Lee, Kyunghwan Kim, Hye-Jin Jeong, Subin Choi, Himchan Cheng, Dayoung Kim, Soomin Heo, Jinhee Mun, Minjong Kim, Eunjin Lee, Yoon Ji Choi, Seon-Gyeong Lee, Eun A Lee, Yewon Jang, Kayeong Lim, Heon Seok Kim, Euihwan Jeong, Seung-Jae Myung, Deok-Beom Jung, Chang Sik Yu, In Ho Song, M Ryan Corces, Joo H Kang, Kyungjae Myung, Taejoon Kwon, Tae-Eun Park, Jinmyoung Joo, Seung Woo Cho

Affiliations

  • Center for Genomic Integrity, Institute for Basic Science, Ulsan, Republic of Korea.
  • Department of Biomedical Engineering, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea.
  • Department of Chemistry, College of Natural Science, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea.
  • Department of Biological Science, College of Information and Biotechnology, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea.
  • In Vivo Research Center, UNIST Central Research Facilities, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea.
  • Division of Research and Development, CasCure Therapeutics, Seoul, Republic of Korea.
  • Brain Science Institute, Korea Institute of Science and Technology, Seoul, Republic of Korea.
  • Department of Life Science, College of Natural Science, Hanyang University, Seoul, Republic of Korea.
  • CasCure Therapeutics, Ulsan, Republic of Korea.
  • Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
  • Digestive Diseases Research Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
  • EDIS Biotech, Seoul, Republic of Korea.
  • Division of Colon and Rectal Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
  • Gladstone Institute of Neurological Disease, San Francisco, California.
  • Gladstone Institute of Data Science and Biotechnology, San Francisco, California.
  • Department of Neurology, University of California San Francisco, San Francisco, California.
  • Graduate School of Health Science and Technology, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea.

MeSH

Cells, Poly(Adp-Ribose) Polymerase Inhibitors, Clustered Regularly Interspaced Short Palindromic Repeats, Poly(Adp-Ribose) Polymerases, Neoplasms, Poly Adenosine Diphosphate Ribose, Therapeutics, Genes, Brca2, Endonucleases, Cell Death

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