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Publications

Journal Article Epublish 6 citations

PubMed: 40341225 DOI: 10.1038/s41598-025-00354-2

National trends in dyslipidemia prevalence, awareness, treatment, and control in South Korea from 2005 to 2022.

Sci Rep 15(1):16148

Authors: Hyeseung Lee, Seokjun Kim, Yejun Son, Soeun Kim, Hyeon Jin Kim, Hyesu Jo, Jaeyu Park, Kyeongmin Lee, Hayeon Lee, Jiseung Kang, Selin Woo, Sunyoung Kim, Sang Youl Rhee, Jiyoung Hwang, Lee Smith, Dong Keon Yon

Affiliations

  • Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea. Center for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea.
  • Center for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea. Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.
  • Center for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea. Department of Regulatory Science, Kyung Hee University, Seoul, South Korea.
  • Center for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea. Department of Electronics and Information Convergence Engineering, Kyung Hee University, Yongin, South Korea.
  • Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA. Department of Health and Safety Convergence Science, Korea University Graduate School, Seoul, South Korea.
  • Department of Family Medicine, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.
  • Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea. Center for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea. Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea. Department of Regulatory Science, Kyung Hee University, Seoul, South Korea. Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, South Korea.
  • Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea. Center for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea.
  • Centre for Health, Performance and Wellbeing, Anglia Ruskin University, East Rd, Cambridge, CB1 1PT, UK.
  • Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea. Center for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea. Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea. Department of Regulatory Science, Kyung Hee University, Seoul, South Korea. Department of Pediatrics, College of Medicine, Kyung Hee University Medical Center, Kyung Hee University, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea.

Abstract

Dyslipidemia has steadily increased in South Korea over the past two decades, emerging as a major public health concern and key risk factor for cardiovascular disease. Thus, our study aimed to investigate long-term trends in the prevalence, awareness, treatment, and control of dyslipidemia in South Korea, including the COVID-19 pandemic. This study utilized data from nationally representative cross-sectional surveys conducted as part of the Korea National Health and Nutrition Examination Survey from 2005 to 2022, analyzing long-term trends of dyslipidemia among 98,396 individuals aged over 30. Weighted linear and binary logistic regression were performed to calculate the β coefficients, β diff, and weighted odds ratios with 95% confidence intervals (CIs). Weighted odds ratios were computed for various socioeconomic groups using aggregated data from 2005 to 2022. The prevalence of dyslipidemia increased from 41.30% (95% CI 40.40-42.21) in 2005-2009 to 48.41% (47.36-49.47) in 2020-2022. Awareness increased from 17.87% (16.75-18.99) to 48.90% (47.34-50.47), treatment from 7.10% (6.39-7.80) to 38.19% (36.61-39.76), and control among prevalence from 6.49% (5.79-7.19) to 31.82% (30.33-33.32). Treatment (β diff, 3.94 [1.97-5.92]) and control among prevalence (β diff, 3.52 [1.67-5.38]) increased more rapidly during the pandemic. Higher odds of dyslipidemia were associated with male sex, older population, rural residence, high BMI, central adiposity, low education and income levels, smoking, and high-risk alcohol consumption. Lower odds of awareness, treatment, and control among individuals with dyslipidemia were associated with male sex, younger population, rural residence, higher education and income levels, smoking, and high-risk alcohol consumption. Over the past 18 years, the prevalence, awareness, treatment, and control of dyslipidemia have steadily increased, with persistent disparities among socioeconomic groups.

MeSH

Dyslipidemias, Income, Odds Ratio, Prevalence, Sex, Pandemics, Natural Science Disciplines, Therapeutics, Education, Smoking, Alcohol Drinking