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Publications

Letter Review Ppublish

PubMed: 40436147 DOI: 10.1016/j.mocell.2025.100233

Brief guide to assays for measuring health parameters using Caenorhabditis elegans.

Mol Cells 48(8):100233

Authors: Seungjae Hwang, Jongsun Lee, Seung-Jae V Lee

Affiliations

  • Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea.
  • Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea.

Abstract

Assessing health parameters is essential for understanding the decline of physiological functions during aging. The nematode Caenorhabditis elegans serves as a powerful model in aging research. This paper introduces representative methods for evaluating health parameters using C. elegans and provides quantitative indicators of functional declines during aging. This manuscript will be useful for researchers unfamiliar with healthspan studies using C. elegans and may help perform physiological experiments for healthy aging.

MeSH

Cells, Aging, Stress, Physiological, Research

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