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Publications

Journal Article Comparative Study Epublish

PubMed: 40445078 DOI: 10.21470/1678-9741-2024-0071

Del Nido vs. Blood Cardioplegia: A Comparative Analysis of Postoperative Atrial Fibrillation in Coronary Artery Bypass Grafting Patients.

Braz J Cardiovasc Surg 40(3):e20240071

Authors: Hasan Toz, Ali Aycan Kavala, Saygın Türkyılmaz, Yusuf Kuserli, Gülsüm Türkyılmaz, Mehmet Ali Yesiltas, Necdet Kılıçaslan

Affiliations

  • Department of Cardiovascular Surgery, Bakırköy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.
  • Department of Cardiovascular Surgery, ISTUN Sisli Kolan International Hospital, Istanbul, Turkey.

Abstract

INTRODUCTION

Cardioplegia solution, also called the del Nido solution, has been widely used in pediatric cardiac surgeries, and has recently started to be used in adult cardiac surgeries. In this context, this study aimed to investigate the relationship between the use of del Nido and blood cardioplegia solutions and postoperative atrial fibrillation rates in our clinic.

METHODS

The study sample comprised 140 patients who underwent coronary artery bypass grafting. The del Nido and blood cardioplegia solutions were used in 70 (50%) patients. The postoperative atrial fibrillation rates of both groups were compared. Additionally, patients' preoperative, intraoperative, and postoperative data were evaluated.

RESULTS

The cardiopulmonary bypass duration and defibrillation rate were lower in the del Nido cardioplegia group than in the blood cardioplegia group (P < 0.001). Atrial fibrillation rates on postoperative days one, five, and 30 were significantly lower in the del Nido cardioplegia group than in the blood cardioplegia group (P < 0.001, P < 0.001, and P = 0.007, respectively).

CONCLUSION

The postoperative atrial fibrillation rate was significantly lower in the del Nido cardioplegia group than in the blood cardioplegia group. In addition, the del Nido cardioplegia solution did not interrupt the surgical flow, thus resulting in less total perfusion, shorter cross-clamping durations, and fewer defibrillation needs. In conclusion, the del Nido cardioplegia solution can be used safely and effectively in coronary artery bypass grafting surgeries.

MeSH

Heart Arrest, Induced, Blood, Arteries, Atrial Fibrillation, Solutions, Coronary Artery Bypass