Journal Article Review Epublish
PubMed: 40509442 DOI: 10.3390/foods14111914
Research Advances in the Synthesis, Metabolism, and Function of Chlorogenic Acid.
Foods 14(11)
Authors: Yuxin He, Shengming Mao, Yingying Zhao, Jing Yang
Affiliations
- Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable, Ministry of Agriculture and Rural Affairs, Collaborative Innovation Center for Efficient and Green Production of Agriculture in Mountainous Areas of Zhejiang Province, College of Horticulture Science, Zhejiang A&F University, Hangzhou 311300, China.
Abstract
Chlorogenic acids (CGAs) are a group of important plant secondary metabolites produced in the phenylpropanoid metabolic pathway; they are formed via the conjugation of caffeic and quinic acids and are widely distributed across different plant species. Renowned for their multifunctional activities-including antioxidant, anti-inflammatory, antimicrobial, anticancer, antidiabetic, and anti-obesity properties-CGAs are versatile natural food additives with diverse industrial applications. This review summarizes five distinct CGA biosynthetic pathways, the structural and regulatory genes involved, and their key biological functions. The insights aim to facilitate a deeper understanding of CGA metabolism and streamline its exploitation in agriculture and human health.
MeSH
Genes, Regulator, Chlorogenic Acid, Research