Journal Article Ppublish 1 citation
PubMed: 40655374 DOI: 10.1007/s12088-024-01220-x
Optimization of in vitro Biofilm Growth of Candida albicans.
Indian J Microbiol 65(2):1361-1365
Authors: Mazen Abdulghani, Gajanan Zore
Affiliations
- School of Life Sciences, Swami Ramanand Teerth Marathwada University, Nanded, MS 431606 India.
- Department of Biotechnology, School of Life Sciences, Central University of Rajasthan, Bandersindri NH 8, Kishangarh Dist, Ajmer, Rajasthan India.
Abstract
Candida albicans cells growing under biofilm form exhibit exceptional resistance towards anti-fungal agents and host immune responses. In this report, we have investigated variables that affect C. albicans biofilm development. Our observations suggest that factors like inoculum density, adhesion time and media composition play important roles in regulating biofilm formations and inoculum density of 1 × 10 7 cells/mL, adhesion for 90 min, and RPMI 1640 were the optimal conditions.
MeSH
Cells, Tissue Adhesions, Growth, Candida Albicans, Biofilms, Candida