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Publications

Journal Article Ppublish

PubMed: 40694515 DOI: 10.1093/cid/ciaf055

Overcoming Vaccine Inequities and Research Gaps in Africa: Challenges and Opportunities Identified During the COVID-19 Pandemic.

Clin Infect Dis 80(Supplement_1):S9-S15

Authors: Cara Lynn Kim, Thaint Thaint Thwe, Ligia M Cruz Espinoza, Jonathan D Sugimoto, Mosoka P Fallah, Hyon Jin Jeon, Raphaƫl Rakotozandrindrainy, Ellis Owusu-Dabo, Abdramane Soura Bassiahi, Octavie Lunguya, Ilesh V Jani, Florian Marks, Birkneh Tilahun Tadesse

Affiliations

  • International Vaccine Institute, Seoul, Republic of Korea.
  • Department of Epidemiology, University of Washington, Seattle, Washington, USA.
  • Research and Innovation, Africa Centers for Disease Control, Addis Ababa, Ethiopia.
  • International Vaccine Institute, Seoul, Republic of Korea. Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, United Kingdom. Madagascar Institute for Vaccine Research, University of Antananarivo, Antananarivo, Madagascar.
  • Madagascar Institute for Vaccine Research, University of Antananarivo, Antananarivo, Madagascar.
  • School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
  • Institut SupĆ©rieur des Sciences de la Population, UniversitĆ© Ouaga II, Ouagadougou, Burkina Faso.
  • Department of Microbiology, Institut National de Recherche BiomĆ©dicale, Kinshasa, Democratic Republic of the Congo.
  • Department of Medical Biology, Microbiology Service, University Teaching Hospital of Kinshasa, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
  • Instituto Nacional de SaĆŗde, Maputo, Mozambique.
  • International Vaccine Institute, Seoul, Republic of Korea. Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, United Kingdom. Madagascar Institute for Vaccine Research, University of Antananarivo, Antananarivo, Madagascar. Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany. The Hong Kong Jockey Club Global Health Institute, Hong Kong Special Administrative Region, China.
  • Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany.
  • Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.

Abstract

Before the onset of the coronavirus disease 2019 (COVID-19) pandemic, the African region already faced a substantial communicable disease burden and a rising prevalence of noncommunicable and chronic conditions. The COVID-19 pandemic has underscored critical vulnerabilities within the health systems in African countries and highlighted the urgent need for self-sufficiency to increase resilience in vaccine manufacturing and clinical trial capacity. In response, substantial efforts are underway to develop vaccine and pharmaceutical manufacturing capabilities across the continent. Ongoing initiatives supported by large donor organizations are aimed at initiating much-needed progress toward greater self-sufficiency in vaccine production in Africa, as coordinated by the Africa Centers for Disease Control. Continued investment, regulatory harmonization, and strengthened international and regional partnerships are essential for Africa to develop sustainable vaccine manufacturing.

MeSH

Vaccines, Covid-19, Research, Pandemics, Communicable Diseases