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Publications

Journal Article Epublish

PubMed: 40700053 DOI: 10.3390/arm93040022

Imaging and Laboratory Results as Predictors of the Course of COVID-19.

Adv Respir Med 93(4)

Authors: Ewelina Tobiczyk, Hanna Maria Winiarska, Daria Springer, Aleksandra Ludziejewska, Ewa Wysocka, Szymon Skoczyński, Szczepan Cofta

Affiliations

  • Department of Pulmonology, Allergology and Pulmonary Oncology, Poznan University of Medical Sciences, 60-569 Poznan, Poland.
  • Department of Laboratory Diagnostics, Poznan University of Medical Sciences, 60-569 Poznan, Poland.
  • Department of Lung Diseases and Tuberculosis, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-752 Katowice, Poland.

Abstract

BACKGROUND

COVID-19 most often affects the respiratory system and may manifest as acute respiratory failure requiring the use of non-invasive respiratory support (NIRS). The aim of this study was to find predictors based on laboratory results and chest computed tomography (CT) scans performed on admission to the hospital indicating the need for NIRS and predicting mortality after hospital discharge.

METHODS

We retrospectively analysed data from consecutive patients hospitalised in the Pulmonology Department of the Temporary COVID Hospital in Poznan from 1 February 2021 to 31 March 2022. Upon admission to the department, the patients underwent a series of laboratory blood tests and high-resolution chest CT scan.

RESULTS

The study group included 282 patients, with an average age of 60.0 ± 15.0 years. In total, 54 (53%) patients of 101 requiring NIRS died from various causes or required intubation. Patients who required NIRS were significantly older and had more severe changes in the lung parenchyma. They had higher white blood cell and neutrophil counts and lower lymphocyte counts, as well as higher concentrations of D-dimer, CRP, PCT, and IL-6 and greater activities of LDH and AST.

CONCLUSIONS

Laboratory tests and chest CT performed on hospital admission may be useful to rapidly identify patients at higher risk for severe disease.

MeSH

Laboratories, Blood, Covid-19, Continuous Positive Airway Pressure