Editorial Introductory Journal Article Epublish
PubMed: 40789568 DOI: 10.14336/AD.2025.10731
Mitochondrial Dysfunction in Aging and Age-related Disorders.
Aging Dis 16(5):2495-2497
Authors: Aida Adlimoghaddam
Affiliations
- Department of Neurology, Dale and Deborah Smith Center for Alzheimer's Research and Treatment, Neuroscience Institute, Southern Illinois University School of Medicine, Springfield, Illinois, USA.
- Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, Illinois, USA.
- Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, Illinois, USA.
Abstract
Mitochondrial dysfunction is increasingly recognized as a unifying mechanism underlying aging and a wide range of age-related diseases. This special issue brings together recent advances that elucidate how impaired mitochondrial function contributes to neurodegenerative, cardiovascular, and metabolic disorders. The featured articles highlight molecular pathways of mitochondrial decline, its systemic consequences, and potential interventions aimed at restoring mitochondrial health. Collectively, these studies reinforce the concept that targeting mitochondrial integrity holds significant promise for promoting healthy aging and preventing chronic disease.
MeSH
Aging