Publications

Journal Article Epublish

PubMed: 40804920 DOI: 10.3390/diagnostics15151957

Mucinous Carcinoma, Mucinous Borderline Tumor and Pseudomyxoma Ovarii in a Cystic Teratoma: A Histological Conundrum.

Diagnostics (Basel) 15(15)

Authors: Cinzia Giacometti, Mariateresa Mirandola, Camillo Aliberti, Filippo Molinari, Lisa Marcolini, Daniele Mautone, Guido Martignoni

Affiliations

  • Pathology Unit, Pederzoli Hospital, Peschiera del Garda, 37019 Verona, Italy.
  • Gynecology & Obstetrics Unit, Pederzoli Hospital, Peschiera del Garda, 37019 Verona, Italy.
  • Radiology Unit, Pederzoli Hospital, Peschiera del Garda, 37019 Verona, Italy.
  • Academic Unit of Obstetrics and Gynecology, IRCSS Hospital Polyclinic San Martino, 16132 Genoa, Italy.
  • Pathology Unit, Department of Diagnostic and Public Health, University of Verona, 37126 Verona, Italy.

Abstract

Mature teratomas account for approximately 20% of all ovarian tumors identified in pathological studies. Benign or malignant somatic neoplasms developing within teratomas can arise from any tissue in up to 2% of mature cystic teratomas, including low-grade malignant mucinous neoplasms. This report presents the case of a 34-year-old woman with no previous gynecological or general health issues, who was admitted to our Hospital after an asymptomatic pelvic mass was detected during a routine exam. A transvaginal ultrasound revealed a unilateral pelvic mass in the left adnexal region, measuring 8 cm. The CT scan showed a cystic-appearing formation measuring nearly 12 cm, which indented the bladder dome. Final diagnosis indicated a mucinous carcinoma arising from a mucinous borderline lesion within the context of a mature ovarian teratoma. No other involvement or lymphadenopathies were detected on 18FDG-PET CT scan, and the patient is now well and free of recurrences.

MeSH

Adenocarcinoma, Mucinous, Ovary, Neoplasms, Positron Emission Tomography Computed Tomography, Teratoma