Journal Article Review Comparative Study Epublish
PubMed: 40806489 DOI: 10.3390/ijms26157360
Comparative Analysis of the Antioxidant and Anti-Inflammatory Effects of Krill and Fish Oil.
Int J Mol Sci 26(15)
Authors: Esra Tansu Sarıyer, Murat Baş, Meral Yüksel
Affiliations
- Department of Nutrition and Dietetics, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.
- Department of Nutrition and Dietetics, Faculty of Health Science, University of Health Sciences, 34668 Istanbul, Turkey.
- Department of Nutrition and Dietetics, Faculty of Health Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.
- Department of Medical Laboratory Techniques, Vocational School of Health-Related Services, Marmara University, 34865 Istanbul, Turkey.
Abstract
Krill oil (KO) and fish oil (FO) are rich sources of long-chain polyunsaturated fatty acids, with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) bound to distinct molecular carriers (phospholipids vs. triglycerides). These oils have been the subject of considerable research interest over the past few years owing to their roles extensively studied for their antioxidant and anti-inflammatory properties relevant to disease prevention and therapy in certain diseases. This review aimed to provide a comparative summary of the antioxidant and anti-inflammatory activities of KO and FO, based on their bioactive components, and highlight the similarities and differences in their prospective mechanisms of action. Both oils exert antioxidant and anti-inflammatory activities, aligning with the review focus. The bioactivities of both oils stem from their distinct molecular compositions: KO delivers EPA/DHA via phospholipids, alongside astaxanthin, while FO provides EPA/DHA bound to triglycerides. In some cases, they exhibit similar outcomes, whereas in others, one may be more effective than the other. Further comparative studies examining dose-dependent effects, bioavailability kinetics, and tissue-specific molecular pathways are warranted.
MeSH
Oils, Fish Oils, Antioxidants, Triglycerides, Phospholipids