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Journal Article Review Ahead of print

PubMed: 40961758 DOI: 10.1016/j.canrad.2025.104725

Role of radiotherapy in the treatment of primary vaginal cancer: Recommendations of the Société française de radiothérapie oncologique, 2025 update.

Cancer Radiother 29(7-8):104725

Authors: Cyrus Chargari, Anne Ducassou, Camille Roukoz, François Lucia, Adeline Petit, Abel Cordoba, Caroline Lafond, Sophie Renard, Alexandre Escande

Affiliations

  • Radiation Oncology Department, centre hospitalier universitaire Pitié Salpêtrière, Assistance publique-Hôpitaux de Paris, Sorbonne Université, Paris, France.
  • Department of Radiation Oncology, IUCT-oncopole, institut Claudius-Regaud, Toulouse, France.
  • Département de radiothérapie et curiethérapie, centre Léon-Bérard, Lyon, France.
  • Radiation Oncology Department, centre hospitalier universitaire de Brest, Brest, France; LaTIM, Inserm, UMR 1101, université de Brest, 29200 Brest, France.
  • Radiotherapy Department, institut Bergonié, 33000 Bordeaux, France.
  • Department of Radiation Oncology, centre de lutte contre le cancer Oscar-Lambret, Lille, France.
  • Département de radiothérapie, centre Eugène-Marquis, rue de la Bataille-Flandres-Dunkerque, CS 44229, 35042 Rennes cedex, France; Inserm U1099, 35000 Rennes, France; LTSI, université Rennes-1, 35000 Rennes, France.
  • Radiation Oncology Department, Institut de cancérologie de Lorraine Alexis-Vautrin, Vandœuvre-lès-Nancy, France.
  • Radiotherapy Department, centre Léonard-de-Vinci Cancer, Dechy, France.

Abstract

Primary vaginal cancers are rare tumours, for which external beam radiotherapy and brachytherapy are major treatment tools. Given the complexity of brachytherapy techniques, the treatment should be performed in specialised centres. We present the 2025 update of recommendations of the Société française de radiothérapie oncologique on the indications and techniques for external beam radiotherapy and brachytherapy for primary vaginal cancer.

MeSH

Radiotherapy, Brachytherapy, Neoplasms, Vaginal Neoplasms, Therapeutics