Journal Article Ahead of print
PubMed: 41260395 DOI: 10.1016/j.accpm.2025.101681
Efficacy of Ultrasound-Guided Internal Jugular Vein versus Subclavian Vein Cannulation in Neonates and Infants Weighing Less Than 5 kg: A Prospective, Randomized Controlled Trial.
Anaesth Crit Care Pain Med
Authors: Khaled Sarhan, Omar Abdelgawad, Bassant Abdelhamid, Hossam El-Ashmawi, Dina Soliman, Dina Turki, Hebatallah Salah, Mahmoud Badry
Affiliations
- Department of anesthesia and critical care medicine, Cairo university, Cairo, Egypt.
- Department of anesthesia and critical care medicine, Cairo university, Cairo, Egypt.
Abstract
BACKGROUND
This study compared ultrasound-guided supraclavicular subclavian vein (SCV) cannulation and internal jugular vein (IJV) cannulation in neonates and infants weighing less than 5 kg.
METHODS
A total of 108 neonates and infants were randomly assigned to either the SCV group (n = 54) or the IJV group (n = 54). The primary outcome was the success rate on the first insertion attempt. Secondary outcomes included procedure times, adverse events, and other characteristics of venous cannulation.
RESULTS
In neonates and infants weighing less than 5 kg, the SCV group demonstrated a significantly higher first-attempt success rate compared to the control group [43 (79.6%) vs. 30 (55.6%), relative risk (95% CI): 0.7 (0.53-0.92), p =  0.007]. Additionally, the SCV group experienced fewer adverse events (5.6 % vs. 29.6%, p =  0.002).
CONCLUSION
Ultrasound-guided SCV cannulation resulted in a significantly higher first-attempt success rate and a lower incidence of adverse events compared to IJV cannulation in neonates and infants weighing under 5 kg. These findings indicate that SCV cannulation may offer a preferable approach for improving success rates.
REGISTRATION
ClinicalTrial.gov(NCT05956028).
MeSH
Anesthesia, Infant, Newborn, Drug-Related Side Effects And Adverse Reactions, Subclavian Vein, Jugular Veins, Veins, Infant