Publications

Journal Article Case Reports Epublish

PubMed: 41505508 DOI: 10.2106/JBJS.CC.25.00546

Combined Melorheostosis and Osteopoikilosis: Uncommon Presentation with Sciatic Nerve Neuropathy: A Case Report.

JBJS Case Connect 16(1)

Authors: Ismail Tawfeek Badr, Mohamed Kamal Mesregah, Sanjiv Rampal, Mahmoud Mohamed Moawad, Bahaa Zakarya Hasan

Affiliations

  • Department of Orthopaedic Surgery, Menoufia University Faculty of Medicine, Shebin-El-Kom, Menoufia, Egypt.
  • Department of Orthopedic and Traumatology, School of Medicine, International Medical University, Kuala Lumpur, Malaysia.
  • Department of Radiology, Menoufia University Faculty of Medicine, Shebin-El-Kom, Menoufia, Egypt.

Abstract

CASE

A 27-year-old man presented with an 8-year history of chronic right gluteal and posterior thigh pain, worsened by sitting and unresponsive to conservative treatment. Imaging revealed widespread melorheostosis and osteopoikilosis of the right lower extremity, with 2 gluteal soft tissue masses compressing the sciatic nerve. The masses were excised using a dual surgical approach, achieving successful sciatic nerve decompression. Postoperatively, the patient regained normal sitting and sleeping tolerance, with complete pain relief maintained over a 15-month follow-up.

CONCLUSION

Melorheostosis, a rare sclerosing bone disorder sometimes associated with osteopoikilosis, may require surgery when large lesions cause nerve compression.

MeSH

Melorheostosis, Pain, Orthopedics, Osteopoikilosis, Sciatic Nerve