Journal Article Ahead of print
PubMed: 41804082 DOI: 10.1111/eos.70085
Physicochemical and remineralisation properties of calcium silicate and glass ionomer cements applied in simulated caries-affected dentine.
Eur J Oral Sci
Authors: Monika Lukomska-Szymanska, Mateusz Radwanski, Stella Helen Constantinidou, Augusto R Elias Boneta, Umer Daood, Kharouf Naji, Filippo Cardinali, Salvatore Sauro
Affiliations
- Department of General Dentistry, Medical University of Lodz, Lodz, Poland.
- Department of Endodontics, Medical University of Lodz, Lodz, Poland.
- Dental Biomaterials and Minimally Invasive Dentistry, Departamento de Odontología, Facultad de Ciencias de la Salud, Universidad CEU-Cardenal Herrera, Alfara del Patriarca, Valencia, Spain.
- School of Dental Medicine, University of Puerto Rico, San Juan, Puerto Rico.
- Restorative Dentistry Division, School of Dentistry, IMU, Kuala Lumpur, Malaysia.
- Centre for Translational Research (CTR), Institute for Research, Development and Innovation (IRDI), IMU, Kuala Lumpur, Malaysia.
- Department of Biomaterials and Bioengineering, INSERM UMR_S 1121, Strasbourg University, Strasbourg, France.
Abstract
Calcium silicate-based and glass ionomer cements are often used in caries-affected dentine. This study investigated the remineralising and physicochemical properties of two calcium silicates and a glass ionomer cement. Human molars with Class I cavities were subjected to pH cycling to simulate caries lesions. These were restored using two different calcium silicate cements (CTR-MTA or MTA-VOCO) or a glass ionomer cement (GIC). After storage in artificial saliva, Knoop microhardness (KHN) was measured within a 300-µm zone from the interface. Solubility, pH, calcium ion release, scanning electron microscopy (SEM)-energy-dispersive x-ray (EDX) and Fourier-transform infrared spectroscopy (FTIR) analyses were also conducted. Data were statistically analysed with statistical significance set at p < 0.05. Both MTAs promoted greater remineralisation (KHN) compared to GIC. GIC showed the lowest solubility, whereas CTR-MTA demonstrated the highest solubility, followed by MTA-VOCO; the latter had the highest calcium release. Apatite deposition was observed only in the MTA groups (SEM-EDX and FTIR). MTA-VOCO demonstrated superior calcium ion release and increased dentine microhardness, although some signs of collagen degradation were also visible. Clinical relevance: GIC and calcium silicate cements may enhance mineral deposition in caries-affected dentine, though the alkalinity of MTAs might compromise collagen integrity at the bonding interface.
MeSH
Dental Caries, Glass Ionomer Cements, Glass, Dentistry, Collagen, Calcium, Dentin