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Journal Article Review Ahead of print

PubMed: 41913548 DOI: 10.1111/dom.70720

Artificial Intelligence in Diabetes Care.

Diabetes Obes Metab

Authors: Michal Dubský, Michaela Liegertová, Robert Bém, Dominika Sojáková, Vladimíra Fejfarová, Edward B Jude

Affiliations

  • Diabetes Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
  • First Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Faculty of Science, Jan Evangelista Purkyně University, Ústí nad Labem, Czech Republic.
  • Second Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Diabetes Center, Tameside and Glossop Integrated Care NHS Foundation Trust and University of Manchester, Ashton-under-Lyne, Lancashire, UK.

Abstract

BACKGROUND

Diabetes care requires frequent and high-stakes decisions that must be made in the setting of substantial day-to-day physiologic variability. The growing availability of continuous glucose monitoring, connected insulin delivery devices and longitudinal electronic health record data has created an opportunity for algorithm-enabled tools that can synthesise high-frequency data, reduce cognitive burden for patients and clinicians, and support safer and more consistent decision-making.

AIM

In this review, artificial intelligence (AI) is used broadly to describe computational systems that generate predictions, recommendations or automation from clinical data.

METHODS

We distinguish between algorithmic automation and control methods that underpin many currently deployed automated insulin delivery (AID) systems and machine learning-based models, including deep learning and large language models (LLMs), that are increasingly used for pattern recognition, risk prediction and natural language applications.

RESULTS

This distinction is clinically relevant because evidence standards, safety risks and governance needs vary substantially across these categories.

CONCLUSION

This narrative review summarises current and emerging applications of AI in diabetes care with an emphasis on clinical readiness, strength of evidence and implementation considerations. We highlight established applications in AID, emerging approaches that seek greater autonomy and interoperability and newer tools such as LLMs, wearables and digital twin frameworks, focusing on where evidence is strongest, where risks are highest and what safeguards are required for responsible clinical use.

MeSH

Diabetes Mellitus, Intelligence, Language, Insulin, Algorithms, Automation, Learning, Artificial Intelligence, Diabetes Mellitus, Type 1