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Publications

Journal Article Ahead of print

PubMed: 42235929 DOI: 10.14309/ctg.0000000000001053

Mean Arterial Pressure at Admission Predicts 28-day Mortality in Patients with Severe Alcohol-associated Hepatitis.

Clin Transl Gastroenterol

Authors: Meritxell Ventura-Cots, Ana Clemente, Edilmar Alvarado-Tapias, Sujan Ravi, Berta Cuyas, Marion Tanguy, Maria Poca, Marion Jager, Carlos Fernández-Carrillo, Gavin E Arteel, Ares Villagrasa, Anna Aguilar-Amorós, Josepmaria Argemi, Juan G Abraldes, Francisco Bosques, Robert S Brown, Guadalupe Garcia-Taso, Juan Genesca, Bernd Schanbl, Phillipe Mathurin, Alexander Louvet, Michael R Lucey, Debbie L Shawcross, Elisabeth Verna, Samer Gawrieh, Srinivasan Dasarathy, Wanzhu Tu, Patrick S Kamath, Naga P Chalasani, Craig J McClain, Gyongyi Szabo, Qing Tang, Bruce Barton, Laura E Nagy, Vijay H Shah, Arun J Sanyal, Mack C Mitchell, Ashwani K Singal, German Soriano, Pierre Emmanuel Rautou, Ramon Bataller

Affiliations

  • Liver Unit, Vall d'Hebron University Hospital, Vall d'Hebron Institut of Research (VHIR), Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Centro de Investigación Biomédica En Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.
  • Liver Unit, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Universidad Complutense, Madrid, Spain.
  • Department of Gastroenterology and Hepatology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
  • University of Alabama at Birmingham, Birmingham, AL.
  • Centre de Recherche sur l'Inflammation, Université Paris-Cité, Inserm, Paris, France.
  • Université de Paris, AP-HP, Hôpital Beaujon, Service d'Hépatologie, DMU DIGEST, Centre de Référence des Maladies Vasculaires du Foie, FILFOIE, ERN RARE-LIVER, Centre de recherche sur l'inflammation, Inserm, UMR 1149, Paris, France.
  • Department of Gastroenterology and Hepatology, Hospital Universitario Puerta de Hierro-Majadahonda, IDIPHISA, Madrid, Spain.
  • Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Liver Unit and RNA Biology and Therapies Program, Cima Universidad de Navarra, Cancer Center Clínica Universidad de Navarra (CCUN), Pamplona, Spain.
  • Cirrhosis Care Clinic, Division of Gastroenterology (Liver Unit), CEGIIR, University of Alberta, Edmonton, Canada.
  • Hospital Sant José Tecnológico de Monterrey. Universidad Autonoma de Nuevo Leon, Monterrey, México.
  • Division of Gastroenterology and Hepatology, Weill Cornell Medical College, New York, NY.
  • Section of Digestive Diseases, Yale University, New Haven, Connecticut; Section of Digestive Diseases, Department of Veterans Affairs Connecticut Healthcare, West Haven, CT.
  • Department of Medicine, University of California San Diego, La Jolla, CA, USA; Department of Medicine, VA San Diego Healthcare System, San Diego, CA, USA.
  • Service des Maladies de L'appareil Digestif et Unité INSERM, Hôpital Huriez, Lille, France.
  • Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison; WI.
  • Roger Williams Institute of Liver Studies, King's College London, Foundation for Liver Research and King's College Hospital, London, United Kingdom.
  • Division of Digestive and Liver Diseases, Department of Medicine, Columbia College of Physicians and Surgeons, Columbia University Medical Center, New York, NY.
  • Division of Gastroenterology and Hepatology, Indiana University, Indianapolis, IN, United States.
  • Division of Gastroenterology and Hepatology Cleveland Clinic Foundation, Cleveland, OH, United States.
  • Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, IN, United States.
  • Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, United States.
  • Division of Gastroenterology and Hepatology, University of Louisville, Louisville, KY, United States.
  • Division of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, United States.
  • Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, United States.
  • Department of Inflammation and Immunity, Cleveland Clinic, Cleveland, OH, United States.
  • Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, VA, United States.
  • Division of Digestive and Liver Diseases, University of Texas Southwestern, Dallas, TX, United States.
  • Division of Gastroenterology and Hepatology, Louisville School of Medicine, Louisville, Kentucky, USA.
  • Liver Unit, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, IDIBAPS, Barcelona, Spain.

Abstract

A baseline MAP <80 mmHg is an independent predictor of short- and mid-term mortality in patients with AH. Strategies aimed at restoring hemodynamic stability may improve outcomes in this high-risk population.

MeSH

Arterial Pressure, Mortality, Gastroenterology, Prognosis, Hepatitis