Journal Article Ppublish
PubMed: 42240891 DOI: 10.1080/25310429.2026.2684131
Aerobic training versus behavioural intervention to increase physical activity on clinical control of people with moderate-to-severe asthma: A randomised clinical trial.
Pulmonology 32(1):2684131
Authors: David Halen Araújo Pinheiro, Fabiano Francisco de Lima, Vitoria Zacarias Cervera, Yan Anderson Pires de Oliveira, Juliana de Melo Batista Dos Santos, Adriana Claudia Lunardi, Alfredo José da Fonseca, Marcio C Mancini, Regina Maria Carvalho-Pinto, Ronaldo Aparecido da Silva, Celso R F Carvalho
Affiliations
- Department of Physical Therapy, School of Medicine, University of São Paulo, São Paulo, Brazil.
- Medical Clinic Department, Clinics Hospital, University of São Paulo, São Paulo, Brazil.
- Obesity and Metabolic Syndrome, Endocrinology and Metabolic Service of Clinics Hospital, University of São Paulo Medical School, São Paulo, Brazil.
- Pulmonary Division, Heart Institute (InCor), Clinics Hospital, University of São Paulo Medical School - São Paulo, São Paulo, Brazil.
Abstract
BACKGROUND
Aerobic training (AT) or behavioural interventions (BI) to increase physical activity in daily life (PADL) improve clinical control in people with asthma; however, comparisons between these interventions remain poorly known.
OBJECTIVE
To compare the effects of AT versus BI on clinical control in people with moderate to severe asthma in the short- and medium-term.
METHODS
This two-arm, randomised, assessor-blinded trial included physically inactive adults with moderate to severe uncontrolled asthma assigned to either an aerobic training group (ATG, n = 27) or a behavioural intervention group (BIG, n = 25). AT was performed on a treadmill (2x/week;45 min/session), and intensity was determined by a cardiopulmonary exercise test (CPET). BI was based on social cognitive theory (1x/week; 90 min/session). At baseline, post-intervention (short-term), and after 4-month follow-up (medium-term) assessments included clinical control (ACQ), quality of life (AQLQ), anxiety and depression symptoms (HADS), and barriers to PADL.
RESULTS
Most individuals were women, overweight or obese, with anxiety and depression symptoms, and low quality of life. AT and BI improved clinical control, reaching the minimal clinically important difference (MCID) post-intervention, and maintaining it in follow-up (Δ scores of -1.01 vs. -1.46 and -0.57 vs. -0.94, respectively). Furthermore, both groups achieved the MCID for AQLQ after the interventions and at follow-up (Δ scores of 1.33 vs. 1.40 and 0.97 vs. 0.88, respectively).
CONCLUSION
Both interventions yield similar improvements in clinical control and most outcomes. These results suggest that the choice of intervention should be based on the patient's preferences and the intervention centre's capacity to provide care.
MeSH
Depression, Exercise, Quality Of Life, Signs And Symptoms, Asthma