Journal Article Ahead of print 1 citation
PubMed: 42491755 DOI: 10.1039/d6ra04235j
Alginate Micro-fibers encapsulated with oregano essential oil with improved antibacterial efficacy.
RSC Adv
Authors: Abimbola O Orisawayi, Lu Hao, Ishrat J Badruddin, Shivam Tiwari, Maria E Bashawri, Neha Kumawat, Prabhuraj D Venkatraman, Jonathan A Butler, Nicole S Britten, Krzysztof K Koziol, Sameer S Rahatekar
Affiliations
- Composites and Advanced Materials Centre, Faculty of Engineering and Applied Sciences, Cranfield University Bedfordshire MK43 0AL UK.
- Olusegun Agagu University of Science and Technology (OAUSTECH) Okitipupa Ondo State Nigeria.
- Manchester Fashion Institute, Faculty of Arts and Humanities, Manchester Metropolitan University Cavendish Street Manchester M15 6BH UK.
- Department of Life Sciences, Faculty of Science and Engineering, Manchester Metropolitan University Chester Street Manchester M1 5GD UK.
- Composites and Advanced Materials Centre, Faculty of Engineering and Applied Sciences, Cranfield University Bedfordshire MK43 0AL UK. Wolfson School of Mechanical Electrical & Manufacturing Engineering, Loughborough University Leicestershire LE11 3TU UK.
Abstract
Functional biopolymers are being extensively studied for applications in various industries to replace synthetic polymers due to their natural origin and biodegradability. Study investigates, alginate natural oregano essential oil (OEO) fibres at varied concentrations using wet-spinning process. The incorporation of oregano essential oil significantly influenced fibre morphology, with fibre diameter decreasing from 139.57 ± 6.81 µm in the control fibres to 108.43 ± 2.77 µm at 2 wt% OEO (p < 0.0001). The produced fibres exhibited good uniformity across all formulations, as indicated by their low diameter variability. FTIR peaks and TGA data reveal the presence of OEO with alginate. Mechanical tests revealed that with the addition of OEO, tensile strength and Young's modulus of the alginate fibres significantly increased from 69 MPa and 3.3 GPa to 97 MPa and 6.3 GPa, respectively, at 3 wt% OEO loading. The functional wet spun alginate-OEO fibres exhibit antimicrobial properties, with the largest inhibition zones methicillin-resistant Staphylococcus aureus and Listeria monocytogenes, with smaller effects against Salmonella typhimurium and Klebsiella pneumoniae at 2 wt% OEO. This method provides a simple, manufacturing platform to incorporate OEO into alginate while retaining the mechanical and antibacterial properties of the alginate fibres. Our study suggests that the OEO-loaded alginate fibres is suitable for antimicrobial application.
MeSH
Oils, Volatile, Alginates, Polymers