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Publications

Journal Article Epublish

PubMed: 42516945 DOI: 10.1016/j.lana.2026.101404

Initial report from the SAR-TRACK (SELNET) registry: a multicentric international retrospective analysis on the quality of the management of limb and trunk wall soft-tissue sarcomas (2012-2022) in Ibero-American countries.

Lancet Reg Health Am 56:101404

Authors: Javier Martin-Broto, Victor Castro, Antonio Gutierrez, Juan Carlos Haro Varas, Darwin Valentin Salazar-Salazar, Sandro Casavilca, Martin Falla, Andres Rodriguez, Tomas Soule, Yanina Pfluger, Lucia Gonzalez, Maria Lucila Gonzalez Donna, Cinthia Gauna Colas, Maria Luisa Cabañas León, Laura Rojas Scheffer, Fernando Augusto Batista Campos, Felipe D'Almeida Costa, Tomas Mansur Duarte de Miranda Marques, Samuel Aguiar, Claudia Haydee Sarai Caro-Sanchez, Gabriela Concepción Alamilla-Garcia, Kevin F Reyna Perez, Dorian Yarih Garcia-Ortega, Rodolfo Guzman, Natalia Jimenez, Ronald Badilla-Gonzalez, Marco Galvez Villanueva, Mike Maldonado-Meléndez, Gema Aguil, Laura Cantero-Duerksen, Sylvana Soledad Alfonso Recalde, Edith Claros, Ronald Limon, Marina Pacheco, Gisela German, Maria Agustina Tissera, Bruna Bianca Lopes David, Andreia Cristina de Melo, Melisa Camaño, Claudio Victor Silveri Fajardo, Adriana Hernandez, Luis Matamala Rebolledo, Josefina Cruz, Javier Martinez-Trufero, Claudia Valverde, Salvatore Provenzano, Emanuela Palmerini, Armelle Dufresne, Carlos Lopez-Jimenez, Patricio Ledesma … and 4 other authors

Affiliations

  • Research Health Institute of Fundacion Jimenez Diaz (IIS/FJD; UAM), Madrid, Spain.
  • Department of Medical Oncology, Fundacion Jimenez Diaz University Hospital, Madrid, Spain.
  • University Hospital General of Villalba, Madrid, Spain.
  • Medical Oncology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
  • Hematology Department, Son Espases University Hospital, Palma, Spain.
  • Orthopedic Oncology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
  • Pathology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
  • Departamento de cirugía de Mamas, Piel y Tejidos blandos, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
  • Medical Oncology Department, Instituto Alexander Fleming, Buenos Aires, Argentina.
  • Pathology Department, Instituto Alexander Fleming, Buenos Aires, Argentina.
  • Medical Oncology Department, Instituto Nacional del Cáncer, Capiatá, Paraguay.
  • Pathology Department, Instituto Nacional del Cáncer, Capiatá, Paraguay.
  • Medical Oncology Department, A.C. Camargo Cancer Center, São Paulo, Brazil.
  • Pathology Department, A.C. Camargo Cancer Center, São Paulo, Brazil.
  • Surgery Department, A.C. Camargo Cancer Center, São Paulo, Brazil.
  • Pathology Department, Instituto Nacional de Cancerología, Ciudad de Mexico, Mexico.
  • Medical Oncology Department, Instituto Nacional de Cancerología, Ciudad de Mexico, Mexico.
  • Surgery Department, Instituto Nacional de Cancerología, Ciudad de Mexico, Mexico.
  • Pathology Department, Hospital San Juan de Dios, San José, Costa Rica.
  • University of Costa Rica School of Medicine, San José, Costa Rica.
  • Medical Oncology Department, Hospital San Vicente de Paúl, Heredia, Costa Rica.
  • Medical Oncology Department, Hospital Dr. Rafael Angel Calderón Guardia, San Jose, Costa Rica.
  • Medical Oncology Department, Instituto Regional de Enfermedades Neoplásicas del Norte, Trujillo, Peru.
  • Medical Oncology Department, Fundación Centro Oncológico de Integración Regional, Mendoza, Argentina.
  • Medical Oncology Department, Instituto de Previsión Social, Asunción, Paraguay.
  • ONCOS Laboratorio de Patologia, Santa Cruz, Bolivia.
  • Medical Oncology Department, OncoBolivia, Santa Cruz, Bolivia.
  • Pathology Department, Hospital CIDELAS de la Caja del Seguro Social, Panama, Panama.
  • Medical Oncology Department, Hospital Oncológico de la provincia de Córdoba, Cordoba, Argentina.
  • Division of Clinical Research and Technological Development, Brazilian National Cancer Institute (INCA), Rio de Janeiro, Brazil.
  • Medical Oncology Department, National Cancer Institute, Montevideo, Uruguay.
  • Musculoskeletal Oncology Pathology Unit, Traumatology and Orthopedics Clinic of UdelaR at the National Institute of Orthopedics and Traumatology, Montevideo, Uruguay.
  • Orthopedic Oncology, Centro Universitario Contra el Cáncer Hospital Universitario, Monterrey, Mexico.
  • Medical Oncology Department, Instituto Oncológico Fundación Arturo Lopez Perez, Santiago de Chile, Chile.
  • Medical Oncology Department, Canarias University Hospital, San Cristóbal de La Laguna, Spain.
  • Medical Oncology Department, Miguel Servet University Hospital, Zaragoza, Spain.
  • Medical Oncology Department, Vall d'Hebron University Hospital, Barcelona, Spain.
  • Oncology and Hematology Department, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.
  • Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
  • Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA.
  • Medical Oncology Department, Centre León Berard, Lyon, France.
  • Sofpromed Investigación Clínica, S.L. Palma, Spain.

Abstract

BACKGROUND

Multidisciplinary (MDT) management of sarcoma patients, with adherence to clinical practice guidelines (CPG), has a positive impact on patients' outcomes. Sarcoma European & Latin-American Network (SELNET) is an international consortium aiming to improve sarcoma management in Ibero-America. This study presents data from the observational study Sar-Track, which assessed the adherence of SELNET institutions to CPGs. This study aimed to evaluate adherence to established quality indicators in the diagnostic and therapeutic management of patients with soft tissue sarcoma within the SELNET network.

METHODS

Data from sarcoma patients managed in SELNET institutions (2012-2022) were collected. The primary objective was to analyze the adherence to quality factors during diagnosis and treatment, comparing Ibero-American (IA) and Spanish (SP) institutions.

FINDINGS

Data from 1523 localized patients with sarcoma of limbs or trunk-wall were included in this analysis. The median age was 50 (28), with 780 (51%) being female in the whole series. Ethnicity data was not available. Patients managed in IA underwent fewer core biopsies [n = 138 (25%) vs n = 153 (57%), p < 0.0001], fewer magnetic resonance imaging (MRI) [n = 464 (59%) vs 500 (68%), p = 0.003], and fewer MDT discussions before surgery [n = 208 (27%) vs 737 (99.6%), p < 0.0001]. Surgical margin involvement occurred more often in IA cases [n = 215 (27%) vs n = 61 (9%), p < 0.0001], and less radiotherapy was administered in patients from IA [n = 172 (37%) vs n = 185 (62%), p < 0.0001].

INTERPRETATION

This analysis establishes the baseline reality at the initial stage of SELNET, highlighting substantial opportunities for improving adherence to CPGs in Ibero-America.

FUNDING

SELNET was supported by a European Horizon 2020 grant (H2020-SC1-BHC-2018-2020).

MeSH

Registries, Sarcoma, Therapeutics, Tissues