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Publications

Journal Article Ahead of print

PubMed: 42610275 DOI: 10.3324/haematol.2025.300049

Germline EZH2 mutation cooperates with somatic KIT D816V to drive early pediatric advanced systemic mastocytosis.

Haematologica

Authors: Clotilde Devin, Lucas Khellaf, Julien Rossignol, Nathalie Droin, Philippe Drabent, Sylvie Fraitag, Marine Madrange, Christine Leaute-Labreze, Andreas E Kulozik, Stephane Ducassou, Eric Solary, Olivier Hermine, Christine Bodemer, Laura Polivka

Affiliations

  • French reference center on mastocytosis and mast related disorders (CEREMAST), Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris.
  • French reference center on mastocytosis and mast related disorders (CEREMAST), Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France; Department of Hematology, Necker-Cochin Children's Hospital, AP-HP, Paris Centre University, Paris.
  • INSERM UMR 1287, Gustave Roussy Cancer Center, Paris-Saclay University, Villejuif.
  • Department of Pathology, Necker Children's Hospital, AP-HP, Paris Centre University, Paris.
  • Department of Pediatric Dermatology, Pellegrin Children's Hospital Group, Bordeaux University Hospital (CHU de Bordeaux), Bordeaux.
  • Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, Heidelberg.
  • Department of Pediatric Hematology-Oncology, Pellegrin Children's Hospital Group, Bordeaux University Hospital (CHU de Bordeaux), Bordeaux.
  • French reference center on mastocytosis and mast related disorders (CEREMAST), Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France; Department of Dermatology, Reference Center for Rare Skin Disorders in Children, AP-HP, Necker Children's Hospital, Paris Centre University, Paris.
  • French reference center on mastocytosis and mast related disorders (CEREMAST), Imagine Institute, INSERM U1163, AP-HP, Necker Children's Hospital, Paris Centre University, Paris, France; Department of Dermatology, Reference Center for Rare Skin Disorders in Children, AP-HP, Necker Children's Hospital, Paris Centre University, Paris.

MeSH

Mastocytosis, Systemic, Mastocytosis, Mutation