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Publications

Journal Article Ppublish

PubMed: 42617583 DOI: 10.1016/j.ejso.2026.112049

Quality of surgical reporting and adequacy of surgical treatment in salivary gland cancer: a quality assurance ancillary study of the GORTEC 2016-02 SANTAL trial.

Eur J Surg Oncol 52(10):112049

Authors: Juliette Hershkovitch, Benjamin Verillaud, Antoine Moya-Plana, Olivier Malard, Gilles Poissonnet, Audrey Lasne-Cardon, Vianney Bastit, Chloe Bertolus, Philippe Ceruse, Nicolas Fakhry, Sylvie Testelin, Philippe Schultz, Mireille Folia, Jean-Claude Merol, Sylvain Morinière, A Villepelet, Franck Jegoux, Olivier Mauvais, Ludovic De Gabory, Sarah Atallah, Sebastien Vergez, Francois-Regis Ferrand, Juliette Thariat

Affiliations

  • Department of Head and Neck Surgery, Hôpital Tenon, Paris, France.
  • Department of Head and Neck Oncology, Hôpital Lariboisière, Assistance Publique Hôpitaux de Paris, Inserm U1131, Université Paris Cité, Paris, France.
  • Department of Head and Neck Oncology, Gustave-Roussy, Villejuif, France.
  • Department of Head and Neck Surgery. Hotel-Dieu, Nantes University Hospital, Nantes, France.
  • Department of Head and Neck Surgery, Centre Antoine Lacassagne, Nice, France.
  • Department of Head and Neck Surgery, Centre Baclesse, Caen, France.
  • Department of Head and Neck Surgery, CHU de Caen, Caen, France.
  • Department of Maxillo-facial Surgery, Hôpital Pitié-Salpêtrière, Paris, France.
  • Hospices Civils de Lyon Centre Hospitalier Lyon Nord, Lyon, France.
  • Department of Otolaryngology Head and Neck Surgery, AP-HM, France.
  • Department of Maxillo-facial Surgery, CHU Amiens-Picardie, Amiens, France.
  • Department of Head and Neck Surgery, Hôpital Hautepierre, Strasbourg, France.
  • Department of Head and Neck Surgery, CHU, Dijon, France.
  • Department of Head and Neck Surgery CHU, Reims, France.
  • Department of Head and Neck Surgery, CHRU - Hôpital Bretonneau, Tours, France.
  • Department of Head and Neck Surgery, Centre Hospitalier Intercommunal de Créteil, Créteil, France.
  • Department of Maxillo-facial Surgery, CHU, INSERM COSS U1242, Rennes, France.
  • CHU Besançon, Department of Head and Neck Oncology, Besançon, France.
  • Department of Head and Neck Surgery, CHU, Bordeaux, France.
  • Department of Head and Neck Surgery, Hôpital Tenon, Paris, France.
  • Department of Head and Neck Surgery, CHU - Hôpital Larrey, Toulouse, France.
  • Department of Head and Neck Oncology, Gustave-Roussy, Paris, France.
  • Department of Radiotherapy, Centre François Baclesse, Caen, France.

Abstract

INTRODUCTION

In the GORTEC 2016-02 SANTAL randomized trial, patients at intermediate-to-high risk of relapse underwent postoperative radiotherapy ± cisplatin. This ancillary study aimed to evaluate the adequacy of surgery and operative reporting of salivary gland carcinomas (SGC).

MATERIALS AND METHODS

An independent post-hoc analysis of operative and pathological reports was undertaken for 87 patients with salivary gland carcinomas treated at 26 French centers. Surgical quality was assessed with respect to REFCOR guidelines. The quality of operative reporting was investigated. For both, deviations were classified as major, minor, or absent.

RESULTS

Parotid tumors accounted for 53% of cases, submandibular 15%, and minor salivary glands 32% with 37% of adenoid cystic carcinomas. Total or extended parotidectomy was performed in 90.5% of parotid cases, and neck dissection in 70%. Operative reports were rated as adequate in 72% of cases, with 14% minor and 14% major deviations. The rates of inadequate surgical reporting varied between study centers. Surgical procedures were concordant with REFCOR guidelines in 62% of cases, or rated as minor deviations in 22%, 1% as not assessable, and 20% as major deviations, the latter by inadequate neck management or inadequate revision surgery after R2 resection. Quality of reporting by center was correlated with conformity of surgery. Deviations were well balanced between the two trial arms.

CONCLUSION

Deviations from standardized surgical reporting and from REFCOR surgical guidelines were observed. These may influence postoperative radiotherapy planning; their impact on patient outcomes remains to be determined.

MeSH

Radiotherapy, Salivary Glands, Neoplasms, Salivary Gland Neoplasms, Therapeutics, Medical Oncology